BAD

Gene Symbol	BAD
Entrez Gene	572
Alt Symbol	BBC2, BCL2L8
Species	Human
Gene Type	protein-coding
Description	BCL2-associated agonist of cell death
Other Description	BCL-X/BCL-2 binding protein|BCL2-antagonist of cell death protein|BCL2-binding component 6|BCL2-binding protein|bcl-2-binding component 6|bcl-2-like protein 8|bcl-XL/Bcl-2-associated death promoter|bcl2 antagonist of cell death|bcl2-L-8|bcl2-associated agonist of cell death
Swissprots	O14803 Q6FH21 Q92934
Accessions	EAW74233 EAW74234 EAW74235 EAW74236 Q92934 AB451254 BAG70068 AB451378 BAG70192 AF021792 AAB72092 AF031523 AAB88124 AK023420 AK291863 BAF84552 AK303051 BAG64171 AK309150 AW014069 BC001901 AAH01901 BC095431 AAH95431 BE255791 BG435829 BG748336 BT006678 AAP35324 CR541935 CAG46733 CR541959 CAG46757 DQ895784 ABM86710 EU176363 ABW03814 U66879 AAB36516 NM_004322 NP_004313 NM_032989 NP_116784
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. {ECO:0000250}.
Subcellular Location	Mitochondrion outer membrane. Cytoplasm {ECO:0000250|UniProtKB:Q61337}. Note=Colocalizes with HIF3A in the cytoplasm (By similarity). Upon phosphorylation, locates to the cytoplasm. {ECO:0000250|UniProtKB:Q61337}.
Tissue Specificity	Expressed in a wide variety of tissues.
Top Pathways	Apoptosis, Hepatitis C, cGMP-PKG signaling pathway, PI3K-Akt signaling pathway, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PathScan ® Phospho-Bad (Ser112) Sandwich ELISA Antibody Pair - 7842 from Cell Signaling Technology Category Antibody Pair Prices $459.00 Sizes 1 kit (Reagents for 4 x 96 well plates)

PathScan ® Phospho-Bad (Ser112) Sandwich ELISA Kit - 7182 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Total Bad Sandwich ELISA Kit - 7162 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Total Bad Sandwich ELISA Antibody Pair - 7840 from Cell Signaling Technology Category Antibody Pair

Bad pSer75 Human ELISA Kit - ab133984 from Abcam Category ELISA Kit Prices $438.00 Sizes 1 x 96 tests Sensitivity 3 µg/ml Range Sample specific recoverySample typeAverage %RangeCell culture extracts3µg/ml - 200µg/ml

Mouse/Human/Rat Phospho-BAD (Ser91/128) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1316 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 31.25-2000 pg/ml

Mouse/Human/Rat Phospho-BAD (Ser134) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1317 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 31.25-2000 pg/ml

Mouse/Human/Rat BAD ELISA Kit (Cell-Based ELISA) - LS-F1818 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 31.25-2000 pg/ml

Mouse/Human/Rat Phospho-BAD (Ser136) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1459 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 31.25-2000 pg/ml

Mouse/Human/Rat Phospho-BAD (Ser155) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1457 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 31.25-2000 pg/ml

Mouse/Human/Rat Phospho-BAD (Ser112) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1458 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 31.25-2000 pg/ml

Human BAD ELISA Kit (Sandwich ELISA) - LS-F10913 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 31.25-2000 pg/ml

Phospho-Bad, Human/Mouse/Rat, BioAssay™ Cell-Based ELISA Kit (BBC6, BCL2L8) - 145758 from USBiological Life Science Category ELISA Kit

Human/Mouse/Rat Phospho-Bad (S112) Cell-Based ELISA - KCB7517 from R&D Systems Category ELISA Kit

Human Total Bad DuoSet IC ELISA - DYC819-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 125.00 - 8,000 pg/mL

Bcl2 Associated Death Promoter, BAD, Human, ELISA Kit - E-EL-H0561 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 75 Range 125-8000pg/mL

Bcl2 antagonist of cell death (BAD), Human, ELISA Kit - CSB-EL002528HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Bcl2 antagonist of cell death, BAD, Human, ELISA Kit - E15040h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

Bcl-2 Associated Death Promoter, BAD, Mouse, ELISA Kit - E-EL-M0180 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

BCL-2 Associated Death Promoter, BAD, Rat, ELISA Kit - E-EL-R0100 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Bcl2 Associated Death Promoter, BAD, Rabbit, ELISA Kit - E-EL-RB2025 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Bcl2 Associated Death Promoter, BAD, Chicken, ELISA Kit - E-EL-Ch0968 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Bcl2 Associated Death Promoter, BAD, Porcine, ELISA Kit - E-EL-P1792 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Bcl2 Associated Death Promoter, BAD, Monkey, ELISA Kit - E-EL-MK0053 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human BAD ELISA Kit - HB0640 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

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