SUMO4

Gene Symbol SUMO4
Entrez Gene 387082
Alt Symbol IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Species Human
Gene Type protein-coding
Description small ubiquitin-like modifier 4
Other Description SMT3 suppressor of mif two 3 homolog 2|SMT3 suppressor of mif two 3 homolog 4|insulin-dependent diabetes mellitus 5|small ubiquitin-like modifier 4 protein|small ubiquitin-related modifier 4
Swissprots A1L3W5 Q6EEV6
Accessions BAH05006 CAA20019 EAW47808 Q6EEV6 AY340238 AAR04484 BC130305 AAI30306 HQ258040 ADR82794 NM_001002255 NP_001002255
Function Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. {ECO:0000269|PubMed:15123604, ECO:0000269|PubMed:15247916, ECO:0000269|PubMed:16236267}.
Tissue Specificity Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen. {ECO:0000269|PubMed:15123604, ECO:0000269|PubMed:15247916}.
Top Pathways RNA transport

SUMO-4 CRISPR/Cas9 KO Plasmid (h) - sc-403123 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 HDR Plasmid (h) - sc-403123-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 Double Nickase Plasmid (h) - sc-403123-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 Double Nickase Plasmid (h2) - sc-403123-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 CRISPR Activation Plasmid (h) - sc-403123-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 CRISPR Activation Plasmid (h2) - sc-403123-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 Lentiviral Activation Particles (h) - sc-403123-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 Lentiviral Activation Particles (h2) - sc-403123-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SUMO-4 siRNA (h) - sc-106583 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUMO-4 shRNA Plasmid (h) - sc-106583-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUMO-4 shRNA (h) Lentiviral Particles - sc-106583-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUMO-4 siRNA (h2) - sc-270481 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SUMO-4 shRNA Plasmid (h2) - sc-270481-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU129181 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20836 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20836 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SUMO4 siRNA (Human) - CRJ7725 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SUMO4 - MBS8230677 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SUMO4 (NM_001002255.1) - SHH420940 from Creative biogene

Category siRNA
Species Reactivities Human

SUMO4 shRNA Plasmid (Human) - CHJ7725 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SUMO4 miRNA 3'UTR clone - MiUTR1H-10067 from Creative biogene

Species Reactivities Human
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