SUMO4

Gene Symbol SUMO4
Entrez Gene 387082
Alt Symbol IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Species Human
Gene Type protein-coding
Description small ubiquitin-like modifier 4
Other Description SMT3 suppressor of mif two 3 homolog 2|SMT3 suppressor of mif two 3 homolog 4|insulin-dependent diabetes mellitus 5|small ubiquitin-like modifier 4 protein|small ubiquitin-related modifier 4
Swissprots A1L3W5 Q6EEV6
Accessions BAH05006 CAA20019 EAW47808 Q6EEV6 AY340238 AAR04484 BC130305 AAI30306 HQ258040 ADR82794 NM_001002255 NP_001002255
Function Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. {ECO:0000269|PubMed:15123604, ECO:0000269|PubMed:15247916, ECO:0000269|PubMed:16236267}.
Tissue Specificity Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen. {ECO:0000269|PubMed:15123604, ECO:0000269|PubMed:15247916}.
Top Pathways RNA transport

SUMO-2/3/4 (C-3) - sc-393144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUMO-2/3/4 (C-3): sc-393144. Western blot analysis of SUMO-2/3/4 expression in Hep G2 (A) and HeLa (B) whole cell lysates.

SUMO-4 (Z-22) - sc-130885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
SUMO-4 (Z-22): sc-130885. Western blot analysis of SUMO-4 expression in Hep G2 whole cell lysate.

Anti-SUMO4 antibody - ab170850 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast carcinoma tissue, labeling SUMO4 using ab170850 at a 1/50 dilution, followed by peroxidase-conjugation of the secondary antibody and AEC staining.

Anti-SUMO4 antibody - ab119927 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SUMO4 antibody (ab119927) at 1/1000 dilutionLane 1 : HEK293 cell lysateLane 2 : HeLa cell lysateLane 3 : Huma fetal kidney lysateLane 4 : Huma fetal thymus lysate

Anti-SUMO4 antibody - ab68012 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SUMO4 antibody (ab68012) at 1/500 dilutionLane 1 : SUMO4 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SUMO4 antibody [EPR7163] - ab126606 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7163
Overlay histogram showing HEK293 cells stained with ab126606 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab126606, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-SUMO4 Antibody (N-Terminus) - LS-C94886 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (AP) - LS-C246060 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (APC) - LS-C246061 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (FITC) - LS-C246063 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (Biotin) - LS-C246062 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (PE) - LS-C246065 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (AP) - LS-C246066 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (APC) - LS-C246067 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (FITC) - LS-C246069 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (Biotin) - LS-C246068 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (PE) - LS-C246070 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (Azide-free, HRP) - LS-C247909 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (Azide-free, HRP) - LS-C247908 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody - LS-C328805 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody - LS-C328806 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody - LS-C341540 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody (Internal, clone EPR7163) - LS-C152310 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7163
Immunofluorescent staining of HepG2 cells using anti-SUMO4 antibody.

Anti-SUMO4 Antibody (aa2-95) - LS-C178755 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SUMO4 Antibody - LS-C332361 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using SUMO4 Antibody at dilution 1/100.
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