CYP27A1

Gene Symbol	CYP27A1
Entrez Gene	1593
Alt Symbol	CP27, CTX, CYP27
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 27, subfamily A, polypeptide 1
Other Description	5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase|5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase|cholestanetriol 26-monooxygenase|cytochrome P-450C27/25|cytochrome P450 27|cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1|sterol 26-hydroxylase, mitochondrial|sterol 27-hydroxylase|vitamin D(3) 25-hydroxylase
Swissprots	Q02318 A8K303 Q86YQ6 Q6LDB4
Accessions	AAB27199 AAK51672 EAW70653 EAW70654 EAW70655 Q02318 AK226039 AK290418 BAF83107 AK310782 AY178622 AAO21126 BC017044 BC040430 AAH40430 BC051851 AAH51851 M62401 AAA52142 X59812 CAA42481 NM_000784 NP_000775
Function	Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta- cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3- 25-hydroxylase activity.
Subcellular Location	Mitochondrion membrane.
Top Pathways	Primary bile acid biosynthesis, PPAR signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Chlorotoxin full length protein - ab60871 from Abcam Category Protein Prices $251.00 Sizes 40 µg Source E. coli

CYP27A1 peptide - ab139504 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human CYP27A1 full length protein - ab158258 from Abcam Category Protein Source Wheat germ Species Human

CYP27 / CYP27A1 Antibody Blocking Peptide - LS-E18564 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CYP27A1 Protein - H00001593-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CYP27A1 Blocking Peptide - 33R-8744 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CYP27A1 - H00001593-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CYP27A1 - H00001593-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CYP27A1 fusion protein - ag6408 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CYP27A1 fusion protein - Ag7746 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Cytochrome P450 27A1 (CYP27A1) - RPD538Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Cytochrome P450 27A1 Blocking Peptide - CBP1328 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

CYP27A1 (E131) Peptide - BS2192P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

CYP27A1 - TP322953 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CYP27A1 Recombinant Protein Antigen - NBP2-32433PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CYP27A1-Antibody-N-term-Blocking-Peptide - BP2853a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP27A1 Peptide, Human - M34GP03949H from Creative Peptides Category Peptide Source Synthetic. Species Human

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