CYP27A1

Gene Symbol CYP27A1
Entrez Gene 1593
Alt Symbol CP27, CTX, CYP27
Species Human
Gene Type protein-coding
Description cytochrome P450, family 27, subfamily A, polypeptide 1
Other Description 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase|5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase|cholestanetriol 26-monooxygenase|cytochrome P-450C27/25|cytochrome P450 27|cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1|sterol 26-hydroxylase, mitochondrial|sterol 27-hydroxylase|vitamin D(3) 25-hydroxylase
Swissprots Q02318 A8K303 Q86YQ6 Q6LDB4
Accessions AAB27199 AAK51672 EAW70653 EAW70654 EAW70655 Q02318 AK226039 AK290418 BAF83107 AK310782 AY178622 AAO21126 BC017044 BC040430 AAH40430 BC051851 AAH51851 M62401 AAA52142 X59812 CAA42481 NM_000784 NP_000775
Function Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta- cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3- 25-hydroxylase activity.
Subcellular Location Mitochondrion membrane.
Top Pathways Primary bile acid biosynthesis, PPAR signaling pathway

CYP27A1 (G-2) - sc-390974 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP27A1 (G-2): sc-390974. Western blot analysis of CYP27A1 expression in HUV-EC-C (A), Hep G2 (B) and Caco-2 (C) whole cell lysates and human liver tissue extract (D).

CYP27A1 (D-12) - sc-393222 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP27A1 (D-12): sc-393222. Western blot analysis of CYP27A1 expression in Hep G2 (A) and Caco-2 (B) whole cell lysates.

CYP27A1 (H-117) - sc-292976 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CYP27A1 (P-17) - sc-14835 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP27A1 (P-17): sc-14835. Western blot analysis of CYP27A1 expression in non-transfected: sc-117752 (A) and human CYP27A1 transfected: sc-116326 (B) 293T whole cell lysates.

CYP27A1 (T-19) - sc-14836 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP27A1 (T-19): sc-14836. Western blot analysis of CYP27A1 expression in non-transfected: sc-117750 (A), human CYP27A1 transfected: sc-116326 (B) and Hep G2 (C) whole cell lysates.

Anti-CYP27A1 antibody - ab64889 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CYP27A1 antibody (ab64889) at 1/500 dilutionLane 1 : extracts from HeLa cells (5-30µg total protein) Lane 2 : extracts from HeLa cells (5-30µg total protein) and 5-10µg of the immunising peptide.

Anti-CYP27A1 antibody - ab151987 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP27A1 antibody (ab151987) at 1/1000 dilution + A549 whole cell lysate at 30 µg

Anti-CYP27A1 antibody - ab82926 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP27A1 antibody (ab82926) at 1 µg/ml + human fetal brain lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-CYP27A1 antibody - ab89781 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CYP27A1 antibody (ab89781) at 1 µg/ml + Human liver tissue lysate at 50 µg

Anti-CYP27A1 antibody [EPR7529] - ab126785 from Abcam

Prices $388.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7529
All lanes : Anti-CYP27A1 antibody [EPR7529] (ab126785) at 1/1000 dilutionLane 1 : HepG2 lysateLane 2 : Caco 2 lysateLane 3 : Human fetal liver lysateLane 4 : Mouse liver lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CYP27A1 antibody [EPR7529] (HRP) - ab198970 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7529
All lanes : Anti-CYP27A1 antibody [EPR7529] (HRP) (ab198970) at 1/5000 dilutionLane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell LysateLane 2 : Human Fetal Liver (Normal Tissue)Lane 3 : Liver (Mouse) Tissue LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-CYP27A1 antibody - C-terminal - ab197933 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CYP27A1 antibody - C-terminal (ab197933) at 1/200 dilutionLane 1 : Mouse liver tissue lysateLane 2 : Human fetal liver tissue lysateLysates/proteins at 40 µg per lane.

Anti-CYP27 / CYP27A1 Antibody (aa1-531) - LS-C128466 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CYP27 / CYP27A1 Antibody - LS-C310065 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP27 / CYP27A1 Antibody (aa432-481) - LS-C102397 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP27A1 antibody LS-C102397 Western blot of Fetal Brain lysate.

Anti-CYP27 / CYP27A1 Antibody (aa101-150) - LS-C119492 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, using Cytochrome P450 27A1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CYP27 / CYP27A1 Antibody (N-Terminus) - LS-C345325 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CYP27A1 Antibody with human Fetal Liver lysate.

Anti-CYP27 / CYP27A1 Antibody (Glu131) - LS-C176853 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of CYP27A1 (E131) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-CYP27 / CYP27A1 Antibody (Internal, clone EPR7529) - LS-C152403 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR7529
IHC of paraffin-embedded human liver tissue using anti-CYP27A1 antibody.

CYP27A1 Antibody - NBP2-32433 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP27A1 Antibody [NBP2-32433] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

CYP27A1 Antibody - NBP2-16062 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP27A1 Antibody [NBP2-16062] - Sample (50 ug of whole cell lysate) A: Mouse Liver. Diluted at 1:1000.

CYP27A1 Antibody - NBP2-16063 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP27A1 Antibody [NBP2-16063] - Sample (50 ug of whole cell lysate) A: Mouse Liver, 7. 5% SDS PAGE gel, diluted at 1:1000.

CYP27A1 Antibody - H00001593-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: CYP27A1 Antibody [H00001593-B01P] - Analysis of CYP27A1 expression in human liver.

CYP27A1 Antibody - H00001593-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP27A1 Antibody [H00001593-D01] - Expression in transfected 293T cell. Lane 1: CYP27A1 transfected lysate(60.20 KDa). Lane 2: Non-transfected lysate.

CYP27A1 Antibody - 46170002 from Novus Biologicals

Prices $299.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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