CYP27A1

Gene Symbol CYP27A1
Entrez Gene 1593
Alt Symbol CP27, CTX, CYP27
Species Human
Gene Type protein-coding
Description cytochrome P450, family 27, subfamily A, polypeptide 1
Other Description 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase|5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase|cholestanetriol 26-monooxygenase|cytochrome P-450C27/25|cytochrome P450 27|cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1|sterol 26-hydroxylase, mitochondrial|sterol 27-hydroxylase|vitamin D(3) 25-hydroxylase
Swissprots Q02318 A8K303 Q86YQ6 Q6LDB4
Accessions AAB27199 AAK51672 EAW70653 EAW70654 EAW70655 Q02318 AK226039 AK290418 BAF83107 AK310782 AY178622 AAO21126 BC017044 BC040430 AAH40430 BC051851 AAH51851 M62401 AAA52142 X59812 CAA42481 NM_000784 NP_000775
Function Catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta- cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3- 25-hydroxylase activity.
Subcellular Location Mitochondrion membrane.
Top Pathways Primary bile acid biosynthesis, PPAR signaling pathway

CYP27A1 CRISPR/Cas9 KO Plasmid (h) - sc-402836 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 HDR Plasmid (h) - sc-402836-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 Double Nickase Plasmid (h) - sc-402836-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 Double Nickase Plasmid (h2) - sc-402836-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 CRISPR Activation Plasmid (h) - sc-402836-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 CRISPR Activation Plasmid (h2) - sc-402836-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 Lentiviral Activation Particles (h) - sc-402836-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 Lentiviral Activation Particles (h2) - sc-402836-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP27A1 siRNA (h) - sc-41500 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP27A1 shRNA Plasmid (h) - sc-41500-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP27A1 shRNA (h) Lentiviral Particles - sc-41500-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU003991 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6879 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6879 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11993 from Sigma-Aldrich

Category miRNA

CYP27A1 siRNA (Human) - CRH1120 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP27A1 RNAi - H00001593-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CYP27A1 - MBS8217076 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYP27A1 (NM_000784.3) - SHH272969 from Creative biogene

Category siRNA
Species Reactivities Human

Human CYP27A1 siRNA - orb261622 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP27A1 shRNA Plasmid (Human) - CHH1120 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP27A1 miRNA 3'UTR clone - MiUTR3H-08532 from Creative biogene

Species Reactivities Human
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