NR2C1

Gene Symbol	NR2C1
Entrez Gene	7181
Alt Symbol	TR2
Species	Human
Gene Type	protein-coding
Description	nuclear receptor subfamily 2, group C, member 1
Other Description	TR2 nuclear hormone receptor|nuclear receptor subfamily 2 group C member 1|nuclear receptor subfamily 2, group C isoform|orphan nuclear receptor TR2
Swissprots	Q15625 P13056 Q15626 A8K5K4
Accessions	EAW97517 EAW97518 EAW97519 EAW97520 P13056 AB307707 BAH02298 AK291319 BAF84008 BC026074 BC040141 AAH40141 BE676699 DB266298 JF432345 ADZ15562 JQ308177 AFF59487 JQ308178 AFF59488 M21985 AAA36650 M29959 AAA36762 M29960 AAA36761 XM_005269133 XP_005269190 XM_006719584 XP_006719647 XM_006719585 XP_006719648 XM_006719586 XP_006719649 XM_011538716 XP_011537018 XM_011538717 XP_011537019 XR_245956 XR_429114 XR_944699 XR_944700 NM_001032287 NP_001027458 NM_001127362 NP_001120834 NM_003297 NP_003288
Function	Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid- regulated preadipocyte proliferation. {ECO:0000269|PubMed:12093804, ECO:0000269|PubMed:17010934}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407}. Nucleus, PML body {ECO:0000250}. Note=Recruited by HDAC3, after all-trans retinoic acid stimulated MAPK1-mediated Thr-223 phosphorylation, to PML bodies for subsequent sumoylation. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TR2-11 full length protein - ab159745 from Abcam Category Protein Source Wheat germ Species Human

Human TR2-11 protein fragment - ab159746 from Abcam Category Protein Source Wheat germ Species Human

NR2C1 Antibody Blocking Peptide - LS-E3946 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C1 Antibody Blocking Peptide - LS-E10852 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C1 Antibody Blocking Peptide - LS-E10851 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C1 Antibody Blocking Peptide - LS-E13754 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NR2C1 Antibody Blocking Peptide - LS-E13327 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TR2/NR2C1 Protein - H00007181-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TR2/NR2C1 Protein - H00007181-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NR2C1-Antibody-C-term-Blocking-Peptide - BP16146b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NR2C1 - H00007181-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NR2C1 - H00007181-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NR2C1 - H00007181-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NR2C1 - H00007181-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NR2C1 fusion protein - ag5327 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NR2C1 fusion protein - ag4554 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Nuclear receptor subfamily 2 group C member 1(NR2C1) - CSB-YP016051HU CSB-EP016051HU CSB-BP016051HU CSB-MP016051HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NR2C1 Protein - abx164231 from Abbexa Category Protein Species Human, Mouse, Rat

NR2C1 Peptide, Human - M34GP10592H from Creative Peptides Category Peptide Source Synthetic. Species Human

TR2/NR2C1 Recombinant Protein Antigen - NBP2-56277PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nuclear receptor subfamily 2 group C member 1 (NR2C1), Recombinant Protein - MBS954202 from MyBioSource Category Protein Prices $1,395.00, $1,395.00, $1,625.00, $1,625.00, $2,350.00, $2,350.00, $2,795.00, $2,795.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Testicular Receptor 2, Recombinant Protein - MBS2034580 from MyBioSource Category Protein Prices $160.00, $320.00, $495.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Human

Testicular Receptor 2, Recombinant Protein - MBS2034581 from MyBioSource Category Protein Prices $170.00, $345.00, $535.00 Sizes 10 µg, 50 µg, 100 µg Source E Coli Source: Prokaryotic expression Species Mouse

TR2/NR2C1 Recombinant Protein Antigen - NBP2-55133PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

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