MR1

Gene Symbol	MR1
Entrez Gene	3140
Alt Symbol	HLALS
Species	Human
Gene Type	protein-coding
Description	major histocompatibility complex, class I-related
Other Description	MHC class I-like antigen MR-1|MHC class I-related gene protein|MHC class-I related-gene protein|class I histocompatibility antigen-like protein|major histocompatibility complex class I-related gene protein|major histocompatibility complex, class I-like sequence
Swissprots	Q9TQB3 O97986 O97985 Q95HB8 Q95460 Q9MY23 Q9TQB9 Q9TQK3 B4E3B1 Q53GM1 A8K2V9 Q9NPL2
Accessions	AAD02172 AAF40170 EAW91095 EAW91096 EAW91097 EAW91098 Q95460 AF010446 AAD01442 AF010447 AAD01443 AF031469 AAD01933 AJ249778 CAB77667 AK056155 AK222910 BAD96630 AK290374 BAF83063 AK304645 BAG65423 BC012485 AAH12485 DC297418 U22963 AAC50174 XM_006711286 XP_006711349 XM_011509462 XP_011507764 XM_011509463 XP_011507765 NM_001194999 NP_001181928 NM_001195000 NP_001181929 NM_001195035 NP_001181964 NM_001531 NP_001522
Function	Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent. {ECO:0000269|PubMed:12794138, ECO:0000269|PubMed:19416870}.
Subcellular Location	Isoform 3: Cell membrane {ECO:0000269|PubMed:23457030}; Single-pass type I membrane protein {ECO:0000269|PubMed:23457030}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:23457030}. Note=The larger proportion remains in the ER in an immature state. The subset that reach cell surface does it through a B2M-independent pathway.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:7624800}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MR1 (H-63) - sc-292077 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

MR1 (E-13) - sc-104380 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

MR1 (B-3) - sc-377312 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Anti-MR1 antibody - ab55164 from Abcam Prices $376.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-MR1 antibody - C-terminal - ab172985 from Abcam Prices $376.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (clone 5B5) - LS-C139208 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5B5

Anti-MR1 Antibody (aa312-341, AP) - LS-C223321 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341, Biotin) - LS-C223323 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341, APC) - LS-C223322 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341, FITC) - LS-C223324 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341, Azide-free, HRP) - LS-C223325 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa311-341) - LS-C323091 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa52-341) - LS-C311561 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341, PE) - LS-C223326 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MR1 Antibody (aa312-341) - LS-C158294 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

MR1 Antibody (5E9.) - H00003140-M03 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5E9.

MR1 Antibody (5B5) - H00003140-M04 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5B5

MR1 Antibody - H00003140-A01 from Novus Biologicals Host Mouse Clonality Polyclonal

Monoclonal Anti-MR1 antibody produced in mouse - WH0003140M3 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5E9

Monoclonal Anti-MR1 antibody produced in mouse - SAB1403923 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5B5

MR1-Antibody-C-term - AP17332b from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

MR1-Antibody-monoclonal-M03 - AT2898a from Abgent, a WuXi AppTec company Prices $315.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 5E10

MR1 antibody [N1C3] - GTX103714 from GeneTex Prices $149.00 Sizes 100 μl Host Rabbit Clonality Polyclonal

MR1 Antibody - C-terminal region (OAAB12763) - OAAB12763 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

MR1 antibody - H00003140-A01 from Acris Antibodies Prices $300.00 Sizes 50 µl Host Mouse Clonality Polyclonal

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