MR1

Gene Symbol	MR1
Entrez Gene	3140
Alt Symbol	HLALS
Species	Human
Gene Type	protein-coding
Description	major histocompatibility complex, class I-related
Other Description	MHC class I-like antigen MR-1|MHC class I-related gene protein|MHC class-I related-gene protein|class I histocompatibility antigen-like protein|major histocompatibility complex class I-related gene protein|major histocompatibility complex, class I-like sequence
Swissprots	Q9TQB3 O97986 O97985 Q95HB8 Q95460 Q9MY23 Q9TQB9 Q9TQK3 B4E3B1 Q53GM1 A8K2V9 Q9NPL2
Accessions	AAD02172 AAF40170 EAW91095 EAW91096 EAW91097 EAW91098 Q95460 AF010446 AAD01442 AF010447 AAD01443 AF031469 AAD01933 AJ249778 CAB77667 AK056155 AK222910 BAD96630 AK290374 BAF83063 AK304645 BAG65423 BC012485 AAH12485 DC297418 U22963 AAC50174 XM_006711286 XP_006711349 XM_011509462 XP_011507764 XM_011509463 XP_011507765 NM_001194999 NP_001181928 NM_001195000 NP_001181929 NM_001195035 NP_001181964 NM_001531 NP_001522
Function	Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T- cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent. {ECO:0000269|PubMed:12794138, ECO:0000269|PubMed:19416870}.
Subcellular Location	Isoform 3: Cell membrane {ECO:0000269|PubMed:23457030}; Single-pass type I membrane protein {ECO:0000269|PubMed:23457030}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:23457030}. Note=The larger proportion remains in the ER in an immature state. The subset that reach cell surface does it through a B2M-independent pathway.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:7624800}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MR1 protein fragment - ab158661 from Abcam Category Protein Source Wheat germ Species Human

MR1 Antibody Blocking Peptide - LS-E4942 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MR1 Protein - H00003140-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MR1-Antibody-C-term-Blocking-Peptide - BP17332b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MR1 Protein Lysate (APL10295) - APL10295 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MR1 Protein Lysate (APL10296) - APL10296 from Aviva Systems Biology Category Protein Prices $219.00 Sizes 200 µg

MR1 - H00003140-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MR1 - H00003140-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

MR1 fusion protein - Ag3849 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human MR1, GST-tagged - MR1-964H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Major histocompatibility complex class I-related gene protein(MR1) - CSB-YP853268HU CSB-EP853268HU CSB-BP853268HU CSB-MP853268HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MR1 Protein - abx163075 from Abbexa Category Protein Species Human

MR1 - TP320474 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

MR1 Protein Lysate - orb333250 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg

MR1 Peptide, Human - M34GP09696H from Creative Peptides Category Peptide Source Synthetic. Species Human

MR1 Protein Lysate - orb333249 from Biorbyt Category Protein Prices $400.00 Sizes 200 μg Species Human

MR1 Recombinant Protein Antigen - NBP2-57625PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Major histocompatibility complex class I-related gene protein (MR1), Recombinant Protein - MBS1366501 from MyBioSource Category Protein Prices $1,035.00, $1,035.00, $1,265.00, $1,265.00, $1,600.00, $1,600.00, $2,065.00, $2,065.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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