PTBP1

Gene Symbol	PTBP1
Entrez Gene	5725
Alt Symbol	HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB
Species	Human
Gene Type	protein-coding
Description	polypyrimidine tract binding protein 1
Other Description	57 kDa RNA-binding protein PPTB-1|RNA-binding protein|heterogeneous nuclear ribonucleoprotein I|heterogeneous nuclear ribonucleoprotein polypeptide I|hnRNP I|polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I)|polypyrimidine tract-binding protein 1
Swissprots	Q9BUQ0 P26599
Accessions	AAC99798 EAW61152 EAW61153 EAW61154 EAW61155 EAW61156 EAW61157 EAW61158 P26599 AB208910 BAD92147 BC002397 AAH02397 BC004383 AAH04383 BC013694 AAH13694 BC023219 BQ068293 BT006819 AAP35465 X60648 CAA43056 X62006 CAA43973 X65371 CAA46443 X65372 CAA46444 X66975 CAA47386 XM_005259597 XP_005259654 XM_005259598 XP_005259655 XR_244034 XR_244035 NM_002819 NP_002810 NM_031990 NP_114367 NM_031991 NP_114368 NM_175847
Function	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:16179478, ECO:0000269|PubMed:16260624, ECO:0000269|PubMed:21518792}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PTBP1 293T Cell Transient Overexpression Lysate(Denatured) - H00005725-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

PTBP1 overexpression lysate - LY410400 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTBP1 overexpression lysate - LY410401 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTBP1 overexpression lysate - LY419090 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

PTBP1 293 Cell Lysate - 405329 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PTBP1 293 Cell Lysate - 405330 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PTBP1 293 Cell Lysate - 408923 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

PTBP1 Overexpression Lysate (Denatured) - H00005725-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

PTBP1 Overexpression Lysate (Native) - NBL1-14918 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTBP1 Overexpression Lysate (Native) - NBL1-14919 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PTBP1 Over-expression Lysate Product - GWB-AA276B from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PTBP1 Over-expression Lysate Product - GWB-5C7426 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

PTBP1 Over-expression Lysate Product - GWB-23926E from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human PTBP1 Knockdown Stable Cell Line - CSC-DC012636 from Creative biogene Category Cell Line Species Human

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