PTBP1

Gene Symbol	PTBP1
Entrez Gene	5725
Alt Symbol	HNRNP-I, HNRNPI, HNRPI, PTB, PTB-1, PTB-T, PTB2, PTB3, PTB4, pPTB
Species	Human
Gene Type	protein-coding
Description	polypyrimidine tract binding protein 1
Other Description	57 kDa RNA-binding protein PPTB-1|RNA-binding protein|heterogeneous nuclear ribonucleoprotein I|heterogeneous nuclear ribonucleoprotein polypeptide I|hnRNP I|polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I)|polypyrimidine tract-binding protein 1
Swissprots	Q9BUQ0 P26599
Accessions	AAC99798 EAW61152 EAW61153 EAW61154 EAW61155 EAW61156 EAW61157 EAW61158 P26599 AB208910 BAD92147 BC002397 AAH02397 BC004383 AAH04383 BC013694 AAH13694 BC023219 BQ068293 BT006819 AAP35465 X60648 CAA43056 X62006 CAA43973 X65371 CAA46443 X65372 CAA46444 X66975 CAA47386 XM_005259597 XP_005259654 XM_005259598 XP_005259655 XR_244034 XR_244035 NM_002819 NP_002810 NM_031990 NP_114367 NM_031991 NP_114368 NM_175847
Function	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. {ECO:0000269|PubMed:11003644, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:16179478, ECO:0000269|PubMed:16260624, ECO:0000269|PubMed:21518792}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTBP1 full length protein - ab131990 from Abcam Category Protein Source Wheat germ Species Human

Human PTBP1 peptide - ab23105 from Abcam Category Peptide Species Human

Human PTBP1 protein fragment - ab114379 from Abcam Category Protein Source Wheat germ Species Human

PTBP1 peptide - ab173778 from Abcam Category Peptide

PTBP1 Antibody Blocking Peptide - LS-E14738 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTBP1 Antibody Blocking Peptide - LS-E14739 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PTBP1 Antibody Blocking Peptide - LS-E25599 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PTBP1 Protein - H00005725-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human PTBP1 Protein - H00005725-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PTBP1 Partial Recombinant Protein - H00005725-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PTBP1 blocking peptide - GTX25642-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Pig, Rat, Bovine

Human PTBP1 protein - orb246933 from Biorbyt Category Protein Prices $502.00, $774.00, $1,054.00 Sizes 20 μg, 50 μg, 100 μg Species Human

PTBP1 Blocking Peptide - 33R-7938 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTBP1 Blocking Peptide - 33R-4388 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PTBP1 Peptide - AC21-0429-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PTBP1 (PTB) - H00005725-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PTBP1 (PTB) - H00005725-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PTBP1 (PTB) - H00005725-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

PTBP1 (PTB) - H00005725-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PTBP1 (PTB) - H00005725-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PTBP1 (PTB) - H00005725-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PTBP1 (PTB) - H00005725-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PTB Peptide - 46-243P from ProSci Category Peptide Species Human

PTBP1 fusion protein - Ag3277 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PTBP1 - PTBP1-30323TH from Creative Biomart Category Protein Source Wheat germ

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