Gene Symbol | RHOC |
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Entrez Gene | 389 |
Alt Symbol | ARH9, ARHC, H9, RHOH9 |
Species | Human |
Gene Type | protein-coding |
Description | ras homolog family member C |
Other Description | RAS-related homolog 9|oncogene RHO H9|ras homolog gene family, member C|rho cDNA clone 9|rho-related GTP-binding protein RhoC|rhoC GTPase|small GTP binding protein RhoC |
Swissprots | Q6ICN3 P08134 B3KSW1 |
Accessions | CAI61764 EAW56533 EAW56534 EAW56535 EAW56536 EAW56539 P08134 AF085893 AF498972 AAM21119 AK094474 BAG52873 BC007245 AAH07245 BC009177 AAH09177 BC052808 AAH52808 BQ231012 BT019448 AAV38255 BX648784 CA307508 CB851337 CN289691 CR450360 CAG29356 CX872299 DQ893171 ABM84097 DQ896470 ABM87469 L25081 AAC33179 X06821 CAA29969 NM_001042678 NP_001036143 NM_001042679 NP_001036144 NM_175744 NP_786886 |
Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. {ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:20974804}. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cleavage furrow {ECO:0000269|PubMed:16236794}. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. |
RhoC (D40E4) Rabbit mAb - 3430 from Cell Signaling Technology
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pan Ras (F132) - sc-32 from Santa Cruz Biotechnology
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Rho C (C-10) - sc-393090 from Santa Cruz Biotechnology
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Rho C (37) - sc-130339 from Santa Cruz Biotechnology
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Rho C (C-16) - sc-12116 from Santa Cruz Biotechnology
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Rho C (G-12) - sc-26481 from Santa Cruz Biotechnology
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Rho C (K-12) - sc-26480 from Santa Cruz Biotechnology
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Anti-RHOC antibody - ab64659 from Abcam
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Anti-RHOC antibody [2E12] - ab54837 from Abcam
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Anti-RHOC antibody - C-terminal - ab196633 from Abcam
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Anti-RHOC Antibody (aa1-194) - LS-C131905 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, APC) - LS-C239972 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, AP) - LS-C239973 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, Biotin) - LS-C239974 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, FITC) - LS-C239975 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, PE) - LS-C239977 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa35-84) - LS-C102687 from LifeSpan Bioscience
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Anti-RHOC Antibody - LS-C192334 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa102-130, Azide-free, HRP) - LS-C247997 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa1-194, Azide-free) - LS-C328518 from LifeSpan Bioscience
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Anti-RHOC Antibody (aa101-130) - LS-C324664 from LifeSpan Bioscience
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Anti-RHOC Antibody (C-Terminus, clone 6F11) - LS-C339959 from LifeSpan Bioscience
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Anti-RHOC Antibody (C-Terminus, clone 3C6) - LS-C339970 from LifeSpan Bioscience
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Anti-RHOC Antibody (C-Terminus, clone 6B4) - LS-C339969 from LifeSpan Bioscience
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Anti-RHOC Antibody (C-Terminus, clone 3A5) - LS-C339968 from LifeSpan Bioscience
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