NDST4

Gene Symbol NDST4
Entrez Gene 64579
Alt Symbol NDST-4, NHSST4
Species Human
Gene Type protein-coding
Description N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
Other Description N-HSST 4|N-heparan sulfate sulfotransferase 4|bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4|glucosaminyl N-deacetylase/N-sulfotransferase 4
Swissprots Q9H3R1 Q2KHM8
Accessions EAX06309 Q9H3R1 AB036429 BAB18535 AK289670 BAF82359 BC012326 BC113075 AAI13076 BC156696 AAI56697 NM_022569 NP_072091
Function Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity). {ECO:0000250}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

Human NDST4 full length protein - ab163847 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163847 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human NDST4 protein fragment - ab163848 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163848 on a 12.5% SDS-PAGE stained with Coomassie Blue.

NDST4 Antibody Blocking Peptide - LS-E5580 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NDST4 Antibody Blocking Peptide - LS-E17955 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human NDST4 Protein - H00064579-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

NDST4 Recombinant Protein - H00064579-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Species Human

NDST4-Antibody-N-term-Blocking-Peptide - BP18104a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

NDST4 Blocking Peptide - 33R-2334 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

NDST4 Blocking Peptide - 33R-10167 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

NDST4 - H00064579-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

NDST4 - H00064579-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

NDST4 - H00064579-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase - CSB-YP862009HU CSB-EP862009HU CSB-BP862009HU CSB-MP862009HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

NDST4 Recombinant Protein Antigen - NBP1-86481PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

NDST4 Peptide, Human - M34GP10226H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 (NDST4), partial, Recombinant Protein - MBS1481561 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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