CUL9

Gene Symbol	CUL9
Entrez Gene	23113
Alt Symbol	H7AP1, PARC
Species	Human
Gene Type	protein-coding
Description	cullin 9
Other Description	CUL-9|UbcH7-associated protein 1|cullin-9|p53-associated parkin-like cytoplasmic protein|parkin-like cytoplasmic p53 binding protein
Swissprots	Q9BU56 Q8N3W9 Q68CP2 O75188 Q5TCY3 Q8IWT3 Q68D92
Accessions	CCQ43486 EAX04163 EAX04164 Q8IWT3 AB014608 BAA31683 AJ318215 CAC85756 AK125228 BAC86090 AK128364 AK129649 BAC85207 AY145132 AAN61516 AY927523 BC002879 AAH02879 BC017747 BC028159 AAH28159 BC148597 AAI48598 CR749511 CAH18328 CR749841 CAH18696 XM_011514422 XP_011512724 XM_011514423 XP_011512725 XM_011514424 XP_011512726 XM_011514425 XP_011512727 XM_011514426 XP_011512728 XM_011514427 XP_011512729 XM_011514428 XP_011512730 XM_011514429 XP_011512731 XM_011514430 XP_011512732 XR_926122 XR_926123 NM_015089 NP_055904
Function	Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328). {ECO:0000269|PubMed:12526791, ECO:0000269|PubMed:17332328, ECO:0000269|PubMed:24793696}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12526791}.
Tissue Specificity	Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. {ECO:0000269|PubMed:12526791}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PARC protein fragment - ab161538 from Abcam Category Protein Source Wheat germ Species Human

CUL9 / Cullin 9 Antibody Blocking Peptide - LS-E30029 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human PARC Protein - H00023113-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PARC Blocking Peptide - NBP1-77222PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Cullin-9 - H00023113-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Cullin-9 - H00023113-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Cullin-9 Control Peptide - AP30646CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PARC Peptide - 3171P from ProSci Category Peptide Species Human

Recombinant Cullin 9 (CUL9) - RPF360Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human Cullin-9(CUL9) ,partial - CSB-YP815567HU CSB-EP815567HU CSB-BP815567HU CSB-MP815567HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Cullin 9 Protein (Recombinant) - abx166791 from Abbexa Category Protein Source Human Species Human

PARC Recombinant Protein Antigen - NBP1-92243PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CUL9 Peptide, Human - M34GP03845H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Cullin 9 (CUL9) - RPU52272 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

CUL9 Recombinant Protein (OPCD02560) - OPCD02560 from Aviva Systems Biology Category Protein Source E.coli Species Human

PARC Recombinant Protein Antigen - NBP2-58049PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Cullin-9 (CUL9), partial, Recombinant Protein - MBS1316337 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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