CUL9

Gene Symbol CUL9
Entrez Gene 23113
Alt Symbol H7AP1, PARC
Species Human
Gene Type protein-coding
Description cullin 9
Other Description CUL-9|UbcH7-associated protein 1|cullin-9|p53-associated parkin-like cytoplasmic protein|parkin-like cytoplasmic p53 binding protein
Swissprots Q9BU56 Q8N3W9 Q68CP2 O75188 Q5TCY3 Q8IWT3 Q68D92
Accessions CCQ43486 EAX04163 EAX04164 Q8IWT3 AB014608 BAA31683 AJ318215 CAC85756 AK125228 BAC86090 AK128364 AK129649 BAC85207 AY145132 AAN61516 AY927523 BC002879 AAH02879 BC017747 BC028159 AAH28159 BC148597 AAI48598 CR749511 CAH18328 CR749841 CAH18696 XM_011514422 XP_011512724 XM_011514423 XP_011512725 XM_011514424 XP_011512726 XM_011514425 XP_011512727 XM_011514426 XP_011512728 XM_011514427 XP_011512729 XM_011514428 XP_011512730 XM_011514429 XP_011512731 XM_011514430 XP_011512732 XR_926122 XR_926123 NM_015089 NP_055904
Function Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328). {ECO:0000269|PubMed:12526791, ECO:0000269|PubMed:17332328, ECO:0000269|PubMed:24793696}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12526791}.
Tissue Specificity Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. {ECO:0000269|PubMed:12526791}.

PARC CRISPR/Cas9 KO Plasmid (h) - sc-409834 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC HDR Plasmid (h) - sc-409834-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC Double Nickase Plasmid (h) - sc-409834-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC Double Nickase Plasmid (h2) - sc-409834-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC CRISPR Activation Plasmid (h) - sc-409834-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC CRISPR Activation Plasmid (h2) - sc-409834-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC Lentiviral Activation Particles (h) - sc-409834-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC Lentiviral Activation Particles (h2) - sc-409834-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PARC siRNA (h) - sc-44715 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PARC shRNA Plasmid (h) - sc-44715-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PARC shRNA (h) Lentiviral Particles - sc-44715-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU125281 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6779 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6779 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CUL9 siRNA (Human) - CRH8007 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PARC RNAi - H00023113-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CUL9 - MBS8230770 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CUL9 (NM_015089.2) - SHH271917 from Creative biogene

Category siRNA
Species Reactivities Human

CUL9 shRNA Plasmid (Human) - CHH8007 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CUL9 miRNA 3'UTR clone - MiUTR1H-07510 from Creative biogene

Species Reactivities Human
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