CUL9

Gene Symbol CUL9
Entrez Gene 23113
Alt Symbol H7AP1, PARC
Species Human
Gene Type protein-coding
Description cullin 9
Other Description CUL-9|UbcH7-associated protein 1|cullin-9|p53-associated parkin-like cytoplasmic protein|parkin-like cytoplasmic p53 binding protein
Swissprots Q9BU56 Q8N3W9 Q68CP2 O75188 Q5TCY3 Q8IWT3 Q68D92
Accessions CCQ43486 EAX04163 EAX04164 Q8IWT3 AB014608 BAA31683 AJ318215 CAC85756 AK125228 BAC86090 AK128364 AK129649 BAC85207 AY145132 AAN61516 AY927523 BC002879 AAH02879 BC017747 BC028159 AAH28159 BC148597 AAI48598 CR749511 CAH18328 CR749841 CAH18696 XM_011514422 XP_011512724 XM_011514423 XP_011512725 XM_011514424 XP_011512726 XM_011514425 XP_011512727 XM_011514426 XP_011512728 XM_011514427 XP_011512729 XM_011514428 XP_011512730 XM_011514429 XP_011512731 XM_011514430 XP_011512732 XR_926122 XR_926123 NM_015089 NP_055904
Function Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 (PubMed:24793696). Cytoplasmic anchor protein in p53/TP53- associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function (PubMed:12526791, PubMed:17332328). {ECO:0000269|PubMed:12526791, ECO:0000269|PubMed:17332328, ECO:0000269|PubMed:24793696}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:12526791}.
Tissue Specificity Ubiquitously expressed in all tissues with highest expression in testis brain and kidney. {ECO:0000269|PubMed:12526791}.

PARC (Y-15) - sc-33259 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PARC (H-300) - sc-67019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

PARC (C-20) - sc-33260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PARC (NQ-C32) - sc-134412 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PARC (NQ-C32): sc-134412. Western blot analysis of PARC expression in A-431 whole cell lysate.

PARC (PO69) - sc-53748 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
PARC (PO69): sc-53748. Western blot analysis of PARC expression in 293T (A) and HeLa (B) whole cell lysates.

Anti-PARC antibody - ab34847 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PARC antibody - ab115631 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115631 at 5ug/ml staining PARC in Human testis tissue by immunohistochemistry (FFPE). Following primary incubation slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-PARC antibody - ab57032 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PARC antibody - Carboxyterminal end - ab62512 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of PARC in Daudi cells with ab62512 at 2 ug/mL.

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) IHC-plus™ - LS-B401 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CUL9 / Cullin 9 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B401 dilution 1:500.

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) IHC-plus™ - LS-B1386 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CUL9 / Cullin 9 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1386 concentration 5 ug/ml.

Anti-CUL9 / Cullin 9 Antibody (clone PO69) IHC-plus™ - LS-B3911 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone PO69
Anti-CUL9 / Cullin 9 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3911 concentration 10 ug/ml.

Anti-CUL9 / Cullin 9 Antibody - LS-C17194 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (aa2441-2452) - LS-C47410 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (aa900-950) - LS-C93052 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) - LS-C93051 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (aa2503-2517) - LS-C93053 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) - LS-C121276 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (clone 1D4B) - LS-C189748 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-CUL9 / Cullin 9 Antibody (C-Terminus) - LS-C285978 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (aa918-1026, Azide-free) - LS-C330576 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CUL9 / Cullin 9 Antibody (aa1-50) - LS-C287029 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUL9 / Cullin 9 Antibody (aa900-950) - LS-C285977 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Detection of Human PARC by Western Blot and Immunoprecipitation. Samples. Whole cell lysate (40 ug for WB; 500 ug for IP) from untreated U2OS cells or U2OS derived cells that stably express a short hairpin RNA (shPARC) against PARC. Antibody: Affinity purified rabbit anti-PARC antibody used at 0.4 ug/ml for WB and at 2 ug/mg lysate for IP. Normal rabbit IgG was used as a control for immunoprecipitation (IP Control) Detection: Chemiluminescence with an exposure time of 5 minutes.

PARC Antibody - NBP1-77222 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PARC Antibody [NBP1-77222] - Daudi lysate with PARC antibody at (A) 1 and (B) 2 ug/ml.

PARC Antibody - NBP1-02783 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PARC Antibody [NBP1-02783] - Staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Search more