ATP5B

Gene Symbol	ATP5B
Entrez Gene	506
Alt Symbol	ATPMB, ATPSB, HEL-S-271
Species	Human
Gene Type	protein-coding
Description	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
Other Description	ATP synthase subunit beta, mitochondrial|epididymis secretory protein Li 271|mitochondrial ATP synthase beta subunit|mitochondrial ATP synthetase, beta subunit
Swissprots	A8K4X0 P06576 Q14283
Accessions	AAA51808 AAA51809 CBI68016 EAW96952 P06576 AK291085 BAF83774 BC016512 AAH16512 BI561028 DQ403107 ABD77240 DQ891585 ABM82511 DQ894779 ABM85705 FJ224288 ACI45980 X05606 CAA29095 NM_001686 NP_001677
Function	Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Location	Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Top Pathways	Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ATP5B-Over-expression-Lysate - LY11560a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ATP5B 293T Cell Transient Overexpression Lysate(Denatured) - H00000506-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ATP5B 293 Cell Lysate - 400627 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ATPB Overexpression Lysate (Denatured) - H00000506-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ATPB Overexpression Lysate (Native) - NBL1-07817 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ATP5B (h): 293T Lysate - sc-113533 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

ATP5B Over-expression Lysate Product - GWB-BA4400 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ATPB Overexpression Lysate (Denatured) - H00000506-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human ATP5B Knockdown Stable Cell Line - CSC-DC001153 from Creative biogene Category Cell Line Species Human

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