ATP5B

Gene Symbol ATP5B
Entrez Gene 506
Alt Symbol ATPMB, ATPSB, HEL-S-271
Species Human
Gene Type protein-coding
Description ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
Other Description ATP synthase subunit beta, mitochondrial|epididymis secretory protein Li 271|mitochondrial ATP synthase beta subunit|mitochondrial ATP synthetase, beta subunit
Swissprots A8K4X0 P06576 Q14283
Accessions AAA51808 AAA51809 CBI68016 EAW96952 P06576 AK291085 BAF83774 BC016512 AAH16512 BI561028 DQ403107 ABD77240 DQ891585 ABM82511 DQ894779 ABM85705 FJ224288 ACI45980 X05606 CAA29095 NM_001686 NP_001677
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Location Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Top Pathways Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

ATP5B CRISPR/Cas9 KO Plasmid (h) - sc-401009 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B HDR Plasmid (h) - sc-401009-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B Double Nickase Plasmid (h) - sc-401009-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B Double Nickase Plasmid (h2) - sc-401009-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B CRISPR Activation Plasmid (h) - sc-401009-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B CRISPR Activation Plasmid (h2) - sc-401009-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B Lentiviral Activation Particles (h) - sc-401009-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B Lentiviral Activation Particles (h2) - sc-401009-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ATP5B siRNA (h) - sc-40565 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATP5B shRNA Plasmid (h) - sc-40565-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATP5B shRNA (h) Lentiviral Particles - sc-40565-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ATPB RNAi - H00000506-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU029131 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3695 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3695 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ATP5B siRNA (Human) - CRH0352 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATP5B - MBS8240948 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ATP5B(NM_001686.3) - SHG082207 from Creative biogene

Category siRNA
Species Reactivities Human

Human ATP5B siRNA - orb260854 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ATP5B shRNA Plasmid (Human) - CHH0352 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ATP5B miRNA 3'UTR clone - MiUTR1H-00691 from Creative biogene

Species Reactivities Human
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