ATP5B

Gene Symbol ATP5B
Entrez Gene 506
Alt Symbol ATPMB, ATPSB, HEL-S-271
Species Human
Gene Type protein-coding
Description ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
Other Description ATP synthase subunit beta, mitochondrial|epididymis secretory protein Li 271|mitochondrial ATP synthase beta subunit|mitochondrial ATP synthetase, beta subunit
Swissprots A8K4X0 P06576 Q14283
Accessions AAA51808 AAA51809 CBI68016 EAW96952 P06576 AK291085 BAF83774 BC016512 AAH16512 BI561028 DQ403107 ABD77240 DQ891585 ABM82511 DQ894779 ABM85705 FJ224288 ACI45980 X05606 CAA29095 NM_001686 NP_001677
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Subcellular Location Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Top Pathways Alzheimer's disease, Huntington's disease, Oxidative phosphorylation

ATP5B (A-8) - sc-74549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATP5B (A-8): sc-74549. Western blot analysis of ATP5B expression in HeLa whole cell lysate (A) and mouse liver (B) and rat liver (C) tissue extracts.

ATP5B (C-20) - sc-16690 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ATP5B (C-20): sc-16690. Western blot analysis of ATP5B expression in HeLa (A), Caki-1 (B) and DU 145 (C) whole cell lysates.

ATP5B (F-1) - sc-166462 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATP5B (F-1): sc-166462. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ATP5B (H-3) - sc-166443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATP5B (H-3): sc-166443. Western blot analysis of ATP5B expression in non-transfected 293T: sc-117752 (A), human ATP5B transfected 293T: sc-113533 (B) and HeLa (C) whole cell lysates.

ATP5B (E-1) - sc-55597 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ATP5B (E-1): sc-55597. Western blot analysis of ATP5B expression in Caki-1 (A) and JAR (B) whole cell lysates.

ATP5B (H-300) - sc-33618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ATP5B (H-300): sc-33618. Western blot analysis of ATP5B expression in JAR whole cell lysate.

ATP5B (R-20) - sc-16689 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ATP5B (R-20): sc-16689. Western blot analysis of ATP5B expression in HeLa (A), Caki-1 (B), DU 145 (C) and Hep G2 (D) whole cell lysates, mouse (E) and rat (F) liver extracts.

ATP5B (10) - sc-135903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
ATP5B (10): sc-135903. Western blot analysis of ATP5B expression in Jurkat whole cell lysate.

Anti-ATPB antibody - ab85068 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab85068 at 1/100 dilution staining ATPB in human brain by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Note cytoplasmic staining.

Anti-ATPB antibody - ab37922 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal
Anti-ATPB antibody (ab37922) at 1/2000 dilution + E coli-derived fusion protein at 2.5 µgSecondaryGoat anti-IgY-HRP at 1/1000 dilution

Anti-ATPB antibody - ab93643 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ATPB antibody (ab93643) at 1/500 dilutionLane 1 : QGY-7703 cell lysateLane 2 : SMMC-7721 cell lysateLane 3 : PRF-5 cell lysate

Anti-ATPB antibody - ab89632 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-ATPB antibody (ab89632) at 1 µg/ml + Human liver lysate at 50 µg

Anti-ATPB antibody [4.3E8.D10] - ab5432 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4.3E8.D10
Immunocytochemistry/Immunofluorescent analysis of ATPB (red) in HEK293T cells. Cells fixed with 4% formaldehyde were permeabilized and blocked with 1X PBS containing 5% BSA and 0.3% Triton X-100 for 1 hour at room temperature. Cells were probed with ab5432 at 1:100 overnight at 4ºC in 1X PBS containing 1% BSA and 0.3% Triton X-100, washed with 1X PBS, and incubated with a fluorophore-conjugated goat anti-mouse IgG secondary antibody at a dilution of 1:200 for 1 hour at room temperature. Nuclei (blue) were stained with DAPI. Images were taken on a Leica DM1000 microscope at 40X magnification.

Anti-ATPB antibody [EPR11990] - ab170947 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11990
ab170947 showing +ve staining in Human normal kidney tissue.

Anti-ATPB antibody [EPR11991] - ab170948 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11991
Flow cytometric analysis of permeabilized 293 cells labeling ATP5B using ab170948 at 1/10 dilution (red) or a rabbit IgG negative (green).

Anti-ATP5B / ATP Synthase Beta Antibody (clone 6C4) - LS-C114907 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C4
IHC of paraffin-embedded Ovary tissue using anti-ATP5B mouse monoclonal antibody. (Dilution 1:50).

Anti-ATP5B / ATP Synthase Beta Antibody (clone 4E5) - LS-C114906 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E5
IHC of paraffin-embedded pancreas tissue using anti-ATP5B mouse monoclonal antibody. (Dilution 1:50).

Anti-ATP5B / ATP Synthase Beta Antibody (aa135-163) IHC-plus™ - LS-B10700 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-ATP5B / ATP Synthase Beta antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ATP5B / ATP Synthase Beta Antibody (clone 9E3) - LS-C114908 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9E3
IHC of paraffin-embedded liver tissue using anti-ATP5B mouse monoclonal antibody. (Dilution 1:50).

Anti-ATP5B / ATP Synthase Beta Antibody (clone 5G2) - LS-C114923 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5G2
IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ATP5B mouse monoclonal antibody. (Dilution 1:50).

Anti-ATP5B / ATP Synthase Beta Antibody (clone 7F4) - LS-C114921 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7F4
IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-ATP5B mouse monoclonal antibody. (Dilution 1:50).

Anti-ATP5B / ATP Synthase Beta Antibody - LS-C74412 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ATP5B / ATP Synthase Beta Antibody (C-Terminus) - LS-C81177 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-ATP5B / ATP Synthase Beta Antibody (aa142-171, AP) - LS-C218663 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ATP5B / ATP Synthase Beta Antibody (aa142-171, Biotin) - LS-C218664 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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