Gene Symbol | ATP5B |
---|---|
Entrez Gene | 506 |
Alt Symbol | ATPMB, ATPSB, HEL-S-271 |
Species | Human |
Gene Type | protein-coding |
Description | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
Other Description | ATP synthase subunit beta, mitochondrial|epididymis secretory protein Li 271|mitochondrial ATP synthase beta subunit|mitochondrial ATP synthetase, beta subunit |
Swissprots | A8K4X0 P06576 Q14283 |
Accessions | AAA51808 AAA51809 CBI68016 EAW96952 P06576 AK291085 BAF83774 BC016512 AAH16512 BI561028 DQ403107 ABD77240 DQ891585 ABM82511 DQ894779 ABM85705 FJ224288 ACI45980 X05606 CAA29095 NM_001686 NP_001677 |
Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. |
Subcellular Location | Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein. |
Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |
Human ATPB full length protein - ab132136 from Abcam
|
||||||||||
Human ATPB protein fragment - ab92235 from Abcam
|
||||||||||
ATP5B / ATP Synthase Beta Antibody Blocking Peptide - LS-E7232 from LifeSpan Bioscience
|
||||||||||
Recombinant Human ATPB Protein - H00000506-P01 from Novus Biologicals
|
||||||||||
ATP5B-Antibody-Center-Blocking-Peptide - BP2973c from Abgent, a WuXi AppTec company
|
||||||||||
ATP5B Blocking Peptide - 33R-7154 from Fitzgerald
|
||||||||||
ATP5B Blocking Peptide - 33R-6043 from Fitzgerald
|
||||||||||
ATP synthase subunit beta - H00000506-P01-10 from Acris Antibodies
|
||||||||||
ATP synthase subunit beta - H00000506-P01-25 from Acris Antibodies
|
||||||||||
ATPB fusion protein - ag11315 from Proteintech Group
|
||||||||||
ATPB fusion protein - ag11177 from Proteintech Group
|
||||||||||
Recombinant Human ATP5B, His-tagged - ATP5B-26425TH from Creative Biomart
|
||||||||||
Recombinant ATPase, H+ Transporting, Mitochondrial F1 Complex Beta Polypeptide (ATP5b) - RPG387Ra01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Human ATP synthase subunit beta, mitochondrial(ATP5B) - CSB-YP002350HU CSB-EP002350HU CSB-BP002350HU CSB-MP002350HU from Cusabio
|
||||||||||
ATP synthase subunit beta - TP301638 from Acris Antibodies
|
||||||||||
ATP synthase subunit beta, mitochondrial (ATP5B) , Recombinant Protein - MBS964125 from MyBioSource
|
||||||||||
ATP5B, Peptide - MBS428241 from MyBioSource
|
||||||||||
ATPB Recombinant Protein Antigen - NBP1-90816PEP from Novus Biologicals
|
||||||||||
ATPB Recombinant Protein Antigen - NBP1-90815PEP from Novus Biologicals
|
||||||||||
ATP5B Peptide, Human - M34GP01153H from Creative Peptides
|
||||||||||
Human ATP5B protein - orb10177 from Biorbyt
|
||||||||||
Recombinant Human ATP synthase subunit beta, mitochondrial(ATP5B) - RPC20504 from Biomatik
|
||||||||||
ATP5B Recombinant Protein (Human) (OPCA05094) - OPCA05094 from Aviva Systems Biology
|
||||||||||
Recombinant Human ATP synthase subunit beta, mitochondrial(ATP5B),partial - CSB-EP002350HU1 from Cusabio
|
||||||||||
Recombinant Human ATP5F1B Protein (48-529 aa), His-tagged - ATP5F1B-2167H from Creative Biomart
|