PTGDR2

Gene Symbol	PTGDR2
Entrez Gene	11251
Alt Symbol	CD294, CRTH2, DL1R, DP2, GPR44
Species	Human
Gene Type	protein-coding
Description	prostaglandin D2 receptor 2
Other Description	G protein-coupled receptor 44|G-protein coupled receptor 44|chemoattractant receptor homologous molecule expressed on T helper type 2 cells|chemoattractant receptor-homologous molecule expressed on TH2 cells|putative G-protein coupled receptor 44
Swissprots	Q4QRI6 Q9Y5Y4 O94765
Accessions	AAD21055 EAW73902 Q9Y5Y4 AB008535 BAA74518 AF144308 AAD34539 AK291371 BAF84060 AK313849 AY507142 AAR92484 BC096841 AAH96841 NM_004778 NP_004769
Function	Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses. {ECO:0000269|PubMed:11208866, ECO:0000269|PubMed:11535533, ECO:0000269|PubMed:17196174}.
Subcellular Location	Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Internalized receptors colocalized with RAB11A. {ECO:0000269|PubMed:17207480}.
Tissue Specificity	Widespread expression. High expression in stomach, small intestine, heart and thymus. Intermediate expression in colon, spinal cord and peripheral blood and low expression in brain, skeletal muscle and spleen. Expressed also on Th2- and Tc2- type cells, eosinophils and basophils. {ECO:0000269|PubMed:11168006, ECO:0000269|PubMed:11208866, ECO:0000269|PubMed:12466225, ECO:0000269|PubMed:9973380}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

G protein-coupled receptor 44, ELISA Kit - MBS9310756 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The sensitivity of this kit is 0.1 ng/ml. Range 0.5 ng/ml - 16 ng/ml.

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS265269 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS264758 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS2602314 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS262231 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.06 ng/ml. Range 20 ng/ml-0.312 ng/ml

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS268928 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS269708 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime (PGD2-MOX) - MBS260058 from MyBioSource Category ELISA Kit Prices $315.00, $490.00 Sizes 48 strip wells, 96 strip wells

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS268533 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2 receptor, ELISA Kit - MBS288105 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.62-40.0 ng/ml.

Human GPR44 ELISA Kit - E015830 from Biobool Category ELISA Kit Sensitivity The sensitivity of this kit is 0.1 ng/ml.

Human PTGDR2 ELISA Kit - E093024 from Biobool Category ELISA Kit

Prostaglandin D2-methoxime (PGD2-MOX), ELISA Kit - MBS2609652 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2-methoxime, ELISA Kit - MBS2603747 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Prostaglandin D2 receptor, ELISA Kit - MBS760674 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

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