PLXNA2

Gene Symbol PLXNA2
Entrez Gene 5362
Alt Symbol OCT, PLXN2
Species Human
Gene Type protein-coding
Description plexin A2
Other Description plexin 2|plexin-A2|semaphorin receptor OCT|transmembrane protein OCT
Swissprots Q9BRL1 Q96GN9 Q6UX61 B2RMX7 A2RTX9 O75051 Q9UIW1
Accessions EAW93457 O75051 AB007932 BAA32308 AK021813 BAB13902 AK055196 BAB70871 AK094259 AK094367 AK125154 AL544219 AY358496 AAQ88860 BC006193 AAH06193 BC009343 AAH09343 BC032125 BC094835 BC132676 AAI32677 BC136530 AAI36531 DA500239 H11743 X87831 CAB57275 XM_005273164 XP_005273221 XM_005273165 XP_005273222 XM_006711387 XP_006711450 NM_025179 NP_079455
Function Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Detected in fetal brain. {ECO:0000269|PubMed:8570614}.
Top Pathways Axon guidance

Plexin A2 Antibody - 3994 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa cells, mock transfected (lane 1) or transfected with a construct overexpressing Plexin A2 (lane 2), and mouse brain or rat brain using Plexin A2 Antibody.

Plexin A2 (D44D4) Rabbit mAb - 6896 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D44D4
Western blot analysis of extracts from neonatal and adult mouse, and fetal rat brain tissue using Plexin A2 (D44D4) Rabbit mAb.

Plexin A2 (D42B5) Rabbit mAb - 5658 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D42B5
Western blot analysis of extracts from mouse and rat brain tissue using Plexin A2 (D42B5) Rabbit mAb.

plexin-A2 (C-18) - sc-10144 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
plexin-A2 (C-18): sc-10144. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing membrane and cytoplasmic staining of glandular cells.

plexin-A2 (A-2) - sc-393939 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
plexin-A2 (A-2): sc-393939. Western blot analysis of plexin-A2 expression in mouse heart (A) and rat heart (B) tissue extracts.

plexin-A2 (E-1) - sc-166082 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
plexin-A2 (E-1): sc-166082. Western blot analysis of plexin-A2 expression in mouse brain tissue extract.

plexin-A2 (P-16) - sc-10143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plexin-A2 (H-70) - sc-25640 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
plexin-A2 (H-70): sc-25640. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing membrane staining of follicle and non-follicle cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-Plexin A2 antibody - ab39357 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Plexin A2 antibody (ab39357) at 2 µg/ml + Brain (Mouse) Tissue Lysate - normal tissue, 0 days old (ab7188) at 20 µgSecondaryGoat Polyclonal to rabbit IgG - H&L - Pre adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-Plexin A2 antibody - ab88130 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Plexin A2 antibody (ab88130) at 1 µg/ml + recombinant protein (immunogen) at 0.2 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-Plexin A2 antibody - ab192317 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Plexin A2 antibody (ab192317)Lane 1 : A549 whole cell lysateLane 2 : RAW 264.7 whole cell lysateLane 3 : PC12 whole cell lysate

Plexin A2 Antibody [Unconjugated] - AF5486 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

Plexin A2 Antibody (583603) - MAB5486 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 583603

Plexin A2 Antibody - NBP1-59413 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Plexin A2 Antibody [NBP1-59413] - Hela cell lysate, concentration 0.2-1 ug/ml.

Plexin A2 Antibody (2G5) - H00005362-M06 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G5

Plexin A2 Antibody - NBP1-31971 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

Plexin A2 Antibody [Allophycocyanin] - FAB5486A from Novus Biologicals

Prices $359.00
Sizes 100 tests
Host Goat
Clonality Polyclonal

Plexin A2 Polyclonal Antibody - bs-3638R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXNA2 antibody produced in rabbit - SAB4300859 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLXNA2 antibody produced in rabbit - AV49932 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HeLa (<B>Cat. No. AV49932</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1 μg/mL in cell type HeLa

Monoclonal Anti-PLXNA2 antibody produced in mouse - SAB1401287 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G5
<B>Immunoblotting</B><BR/>Monoclonal Anti-PLXNA2, antibody produced in mouse, clone 2G5, purified immunoglobulin: <B>Cat. No. SAB1401287</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~212.66 kDa using PC-12 lysate.

PLXNA2 antibody - N-terminal region (ARP49932_P050) - ARP49932_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Human/Mouse/Rat Plexin A2 Antibody - AF5486 from R&D Systems

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Detection of Mouse Plexin A2 by Simple Western TM . Simple Western lane view shows lysates of bEnd.3 mouse endothelioma cell line, loaded at 0.2 mg/mL. A specific band was detected for Plexin A2 at approximately 246 kDa (as indicated) using 10 µg/mL of Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109 ). This experiment was conducted under reducing conditions and using the 66-440 kDa separation system.
Detection of Mouse and Rat Plexin A2 by Western Blot.Western blot shows lysates of bEnd.3 mouse endothelioma cell line and rat embryonic cortical neuron cells. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat Plexin A2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5486) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for Plexin A2 at approximately 210 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8.

Human/Mouse/Rat Plexin A2 APC-conjugated Antibody - FAB5486A from R&D Systems

Prices $359.00
Sizes 100 tests
Host Goat
Detection of Plexin A2 in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Human/Mouse/Rat Plexin A2 APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB5486A, filled histogram) or isotype control antibody (Catalog # IC108A , open histogram). View our protocol for Staining Membrane-associated Proteins .
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