PLXNA2

Gene Symbol PLXNA2
Entrez Gene 5362
Alt Symbol OCT, PLXN2
Species Human
Gene Type protein-coding
Description plexin A2
Other Description plexin 2|plexin-A2|semaphorin receptor OCT|transmembrane protein OCT
Swissprots Q9BRL1 Q96GN9 Q6UX61 B2RMX7 A2RTX9 O75051 Q9UIW1
Accessions EAW93457 O75051 AB007932 BAA32308 AK021813 BAB13902 AK055196 BAB70871 AK094259 AK094367 AK125154 AL544219 AY358496 AAQ88860 BC006193 AAH06193 BC009343 AAH09343 BC032125 BC094835 BC132676 AAI32677 BC136530 AAI36531 DA500239 H11743 X87831 CAB57275 XM_005273164 XP_005273221 XM_005273165 XP_005273222 XM_006711387 XP_006711450 NM_025179 NP_079455
Function Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Detected in fetal brain. {ECO:0000269|PubMed:8570614}.
Top Pathways Axon guidance

plexin-A2 CRISPR/Cas9 KO Plasmid (h) - sc-403886 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 HDR Plasmid (h) - sc-403886-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 Double Nickase Plasmid (h) - sc-403886-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 Double Nickase Plasmid (h2) - sc-403886-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 CRISPR Activation Plasmid (h) - sc-403886-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 CRISPR Activation Plasmid (h2) - sc-403886-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 Lentiviral Activation Particles (h) - sc-403886-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 Lentiviral Activation Particles (h2) - sc-403886-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

plexin-A2 siRNA (h) - sc-42172 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

plexin-A2 shRNA Plasmid (h) - sc-42172-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

plexin-A2 shRNA (h) Lentiviral Particles - sc-42172-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Plexin A2 RNAi - H00005362-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU119441 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17010 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17010 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLXNA2 siRNA (Human) - CRH3600 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLXNA2 (NM_025179.3) - SHH378200 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLXNA2(NM_025179.3) - SHR105446 from Creative biogene

Category siRNA
Species Reactivities Human

Human PLXNA2 siRNA - orb264102 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PLXNA2 shRNA Plasmid (Human) - CHH3600 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PLXNA2 miRNA 3'UTR clone - MiUTR1H-08019 from Creative biogene

Species Reactivities Human
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