PLXNA2

Gene Symbol	PLXNA2
Entrez Gene	5362
Alt Symbol	OCT, PLXN2
Species	Human
Gene Type	protein-coding
Description	plexin A2
Other Description	plexin 2|plexin-A2|semaphorin receptor OCT|transmembrane protein OCT
Swissprots	Q9BRL1 Q96GN9 Q6UX61 B2RMX7 A2RTX9 O75051 Q9UIW1
Accessions	EAW93457 O75051 AB007932 BAA32308 AK021813 BAB13902 AK055196 BAB70871 AK094259 AK094367 AK125154 AL544219 AY358496 AAQ88860 BC006193 AAH06193 BC009343 AAH09343 BC032125 BC094835 BC132676 AAI32677 BC136530 AAI36531 DA500239 H11743 X87831 CAB57275 XM_005273164 XP_005273221 XM_005273165 XP_005273222 XM_006711387 XP_006711450 NM_025179 NP_079455
Function	Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Detected in fetal brain. {ECO:0000269|PubMed:8570614}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Plexin A2 full length protein - ab114912 from Abcam Category Protein Source Wheat germ Species Human

Human Plexin A2 peptide - ab39355 from Abcam Category Peptide

Mouse Plexin A2 peptide - ab39356 from Abcam Category Peptide

Recombinant Human Plexin A2 Protein - H00005362-P01 from Novus Biologicals Category Protein Prices $369.00, $539.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human OCT protein - orb80745 from Biorbyt Category Protein Prices $170.00, $425.00, $867.00 Sizes 1 mg, 5 mg, 25 mg Species Human

Plexin A2 Blocking Peptide - 33R-8901 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Plexin A2 Blocking Peptide - abx064192 from Abbexa Category Peptide Species Human, Mouse, Rat

Plexin A2 - H00005362-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Plexin A2 - H00005362-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

Plexin A2 - H00005362-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

Plexin A2 - P5884-0.1 from Acris Antibodies Category Protein Prices $630.00 Sizes 100 µg Species Human

Plexin A2 - P5884-1 from Acris Antibodies Category Protein Prices $2,340.00 Sizes 1 mg Species Human

Plexin A2 - P5884-10 from Acris Antibodies Category Protein Prices $255.00 Sizes 10 µg Species Human

Plexin A2 - P5884-50 from Acris Antibodies Category Protein Prices $470.00 Sizes 50 µg Species Human

Octreotide (OCT) - 12-4239-1 from ARP American Research Products Category Peptide Prices $159.00 Sizes 200 µg Source Synthetic peptide

OCT Human - HOPS-272 from NeoScientific Category Protein Prices $65.00, $273.00, $1,170.00 Sizes 1 mg, 5 mg, 25 mg Source NULL Species Human

Human Octreotide - BP000374-HOR-265 from Syd Labs Category Protein Prices $210.00, $900.00 Sizes 5 mg, 25 mg Species Human

OCT Human - GWB-A72F12 from Genway Biotech Category Peptide Prices $75.00, $260.00, $1,075.00 Sizes 1 mg, 5 mg, 25 mg Species Human

Recombinant Human Plexin A2 - PLXNA2-312H from Creative Biomart Category Protein Source Human

Recombinant Human PLXNA2 - PLXNA2-30876TH from Creative Biomart Category Protein Source Wheat germ

OCT - RAB-328 from Reagent Proteins Category Protein Prices $448.00, $1,099.00 Sizes 5 mg, 25 mg Species Human

Plexin A2 Blocking Peptide - CBP2998 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Plexin-A2(PLXNA2) ,partial - CSB-YP018218HU CSB-EP018218HU CSB-BP018218HU CSB-MP018218HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Plexin-A2 (PLXNA2), partial, Recombinant Protein - MBS1242499 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PLXNA2 Peptide, Human - M34GP11988H from Creative Peptides Category Peptide Source Synthetic. Species Human

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