PHF21A

Gene Symbol PHF21A
Entrez Gene 51317
Alt Symbol BHC80, BM-006
Species Human
Gene Type protein-coding
Description PHD finger protein 21A
Other Description BHC80a|BRAF35-HDAC complex protein BHC80|BRAF35/HDAC2 complex (80 kDa)
Swissprots Q9C0G7 Q9H8V9 D3DQP5 Q6AWA2 Q9NZE9 Q9HAK6 Q96BD5
Accessions EAW68012 EAW68013 EAW68014 EAW68015 EAW68016 EAW68017 EAW68018 Q96BD5 AB051483 BAB21787 AF208848 AAF64262 AK021530 BAB13839 AK023258 BAB14492 AL359593 AL359608 AY090777 AAM09095 BC015714 AAH15714 BX648236 CAH10542 CB266669 EU446805 ABZ92334 XM_005252962 XP_005253019 XM_005252965 XP_005253022 XM_006718248 XP_006718311 XM_011520157 XP_011518459 XM_011520158 XP_011518460 XM_011520159 XP_011518461 XM_011520160 XP_011518462 XM_011520161 XP_011518463 XM_011520162 XP_011518464 XM_011520163 XP_011518465 XM_011520164 XP_011518466 XM_011520165 XP_011518467 XM_011520166 XP_011518468 XM_011520167 XP_011518469 XM_011520168 XP_011518470 XM_011520169 XP_011518471 XM_011520170 XP_011518472 XM_011520171 XP_011518473 XM_011520172 XP_011518474 XM_011520173 XP_011518475 XM_011520174 XP_011518476 XM_011520175 XP_011518477 XM_011520176 XP_011518478 XM_011520177 XP_011518479 XM_011520178 XP_011518480 XM_011520179 XP_011518481 XM_011520180 XP_011518482 XM_011520181 XP_011518483 XM_011520182 XP_011518484 XR_930874 NM_001101802 NP_001095272 NM_016621 NP_057705
Function Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. {ECO:0000269|PubMed:16140033}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Highly expressed in brain. Expressed at much lower level in other tissues. {ECO:0000269|PubMed:12032298}.

PHF21A (F-9) - sc-376844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PHF21A (F-9): sc-376844. Western blot analysis of PHF21A expression in SH-SY5Y (A) and IMR-32 (B) nuclear extracts.

PHF21A (G-12) - sc-109845 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PHF21A (G-12): sc-109845. Western blot analysis of PHF21A expression in IMR-32 (A), SK-N-MC (B) and SH-SY5Y (C) nuclear extracts.

PHF21A (H-110) - sc-98761 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-BHC80 / PHF21A antibody - ab41631 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BHC80 / PHF21A antibody (ab41631) at 1 µg/mlLane 1 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 2 : Brain (Mouse) Mouse Tissue LysateLane 3 : Brain (Rat) Rat Tissue LysateLysates/proteins at 10 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-BHC80 / PHF21A antibody - ab129570 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BHC80 / PHF21A antibody (ab129570) at 1/100 dilution + A375 cell line lysate at 35 µg

Anti-BHC80 / PHF21A antibody - ab57354 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57354 BHC80 / PHF21A antibody at 1ug/ml.

Anti-PHF21A / BHC80 Antibody (aa435-464, APC) - LS-C238982 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464, AP) - LS-C238981 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464, Biotin) - LS-C238983 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464, FITC) - LS-C238984 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464, PE) - LS-C238985 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464, Azide-free, HRP) - LS-C248462 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (aa435-464) - LS-C329965 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PHF21A / BHC80 Antibody (N-Terminus) - LS-C110366 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PHF21A antibody LS-C110366 Western blot of HT1080 cell lysate.

Anti-PHF21A / BHC80 Antibody (aa324-373) - LS-C109929 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PHF21A antibody LS-C109929 Western blot of Jurkat lysate.

Anti-PHF21A / BHC80 Antibody - LS-C334645 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell line, using PHF21A antibody.

Anti-PHF21A / BHC80 Antibody (aa436-464) - LS-C163568 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PHF21A Antibody western blot of A375 cell line lysates (35 ug/lane). The PHF21A antibody detected the PHF21A protein (arrow).

Anti-PHF21A / BHC80 Antibody (aa50-100) - LS-C290265 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PHF21A by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from 293T (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), Jurkat (J; 50 ug) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PHF21A antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

PHF21A Antibody - NBP2-04043 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: PHF21A Antibody [NBP2-04043] - Samples: Whole cell lysate from 293T (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), Jurkat (J; 50 ug) and HeLa (H; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PHF21A antibody NBP2-04043 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

PHF21A Antibody - NBP1-92262 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PHF21A Antibody (5A6) - H00051317-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5A6

PHF21A Antibody - H00051317-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PHF21A Antibody [H00051317-A01] - PHF21A polyclonal antibody (A01), Lot # 051214JC01 Western Blot analysis of PHF21A expression in U-2 OS ( Cat # L022V1 ).

Rabbit Anti-BHC80/PHF21A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11452R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-BHC80/PHF21A Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11452R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-BHC80/PHF21A Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11452R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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