PHF21A

Gene Symbol PHF21A
Entrez Gene 51317
Alt Symbol BHC80, BM-006
Species Human
Gene Type protein-coding
Description PHD finger protein 21A
Other Description BHC80a|BRAF35-HDAC complex protein BHC80|BRAF35/HDAC2 complex (80 kDa)
Swissprots Q9C0G7 Q9H8V9 D3DQP5 Q6AWA2 Q9NZE9 Q9HAK6 Q96BD5
Accessions EAW68012 EAW68013 EAW68014 EAW68015 EAW68016 EAW68017 EAW68018 Q96BD5 AB051483 BAB21787 AF208848 AAF64262 AK021530 BAB13839 AK023258 BAB14492 AL359593 AL359608 AY090777 AAM09095 BC015714 AAH15714 BX648236 CAH10542 CB266669 EU446805 ABZ92334 XM_005252962 XP_005253019 XM_005252965 XP_005253022 XM_006718248 XP_006718311 XM_011520157 XP_011518459 XM_011520158 XP_011518460 XM_011520159 XP_011518461 XM_011520160 XP_011518462 XM_011520161 XP_011518463 XM_011520162 XP_011518464 XM_011520163 XP_011518465 XM_011520164 XP_011518466 XM_011520165 XP_011518467 XM_011520166 XP_011518468 XM_011520167 XP_011518469 XM_011520168 XP_011518470 XM_011520169 XP_011518471 XM_011520170 XP_011518472 XM_011520171 XP_011518473 XM_011520172 XP_011518474 XM_011520173 XP_011518475 XM_011520174 XP_011518476 XM_011520175 XP_011518477 XM_011520176 XP_011518478 XM_011520177 XP_011518479 XM_011520178 XP_011518480 XM_011520179 XP_011518481 XM_011520180 XP_011518482 XM_011520181 XP_011518483 XM_011520182 XP_011518484 XR_930874 NM_001101802 NP_001095272 NM_016621 NP_057705
Function Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation. {ECO:0000269|PubMed:16140033}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Highly expressed in brain. Expressed at much lower level in other tissues. {ECO:0000269|PubMed:12032298}.

PHF21A CRISPR/Cas9 KO Plasmid (h) - sc-404494 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A HDR Plasmid (h) - sc-404494-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A Double Nickase Plasmid (h) - sc-404494-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A Double Nickase Plasmid (h2) - sc-404494-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A CRISPR Activation Plasmid (h) - sc-404494-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A CRISPR Activation Plasmid (h2) - sc-404494-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A Lentiviral Activation Particles (h) - sc-404494-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A Lentiviral Activation Particles (h2) - sc-404494-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PHF21A siRNA (h) - sc-96691 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF21A shRNA Plasmid (h) - sc-96691-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF21A shRNA (h) Lentiviral Particles - sc-96691-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PHF21A RNAi - H00051317-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU095881 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16727 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16727 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09210 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09210

PHF21A siRNA (Human) - CRH9694 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PHF21A (NM_016621.3) - SHH374752 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PHF21A(NM_016621.3) - SHR111104 from Creative biogene

Category siRNA
Species Reactivities Human

Human PHF21A siRNA - orb270196 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PHF21A shRNA Plasmid (Human) - CHH9694 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PHF21A miRNA 3'UTR clone - MiUTR1H-07860 from Creative biogene

Species Reactivities Human
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