Gene Symbol | F2RL3 |
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Entrez Gene | 9002 |
Alt Symbol | PAR4 |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor II (thrombin) receptor-like 3 |
Other Description | PAR-4|protease-activated receptor-4|proteinase-activated receptor 4|thrombin receptor-like 3 |
Swissprots | O76067 Q6DK42 Q96RI0 |
Accessions | AAK61908 EAW84566 Q96RI0 AF055917 AAC25699 AF080214 AAC28860 AY431102 AAR08487 BC074782 AAH74782 XM_005260139 XP_005260196 NM_003950 NP_003941 |
Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. {ECO:0000269|PubMed:10079109}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. |
Top Pathways | Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
PAR-4 (C-20) - sc-8464 from Santa Cruz Biotechnology
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PAR-4 (H-120) - sc-25466 from Santa Cruz Biotechnology
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PAR-4 (N-20) - sc-21048 from Santa Cruz Biotechnology
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PAR-4 (A-20) - sc-21049 from Santa Cruz Biotechnology
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Anti-Proteinase Activated Receptor 4 antibody - ab56359 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - ab137927 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - C-terminal - ab139577 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - C-terminal - ab150551 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - Cytoplasmic domain - ab188887 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - Extracellular domain - ab188925 from Abcam
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Anti-Proteinase Activated Receptor 4 antibody - N-terminal - ab188930 from Abcam
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Anti-F2RL3 / PAR4 Antibody (Extracellular Domain) IHC-plus⢠- LS-A1310 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (N-Terminus) IHC-plus⢠- LS-A1308 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (C-Terminus) IHC-plus⢠- LS-A1311 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (aa290-340) - LS-C288851 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (aa19-68) - LS-C200463 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (aa29-78) - LS-C121021 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (aa29-78) - LS-C121101 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (aa48-385) - LS-C314406 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (C-Terminus) - LS-C169971 from LifeSpan Bioscience
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Anti-F2RL3 / PAR4 Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A1309 from LifeSpan Bioscience
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PAR4 Antibody - NBP1-71365 from Novus Biologicals
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PAR4 Antibody - NLS1309 from Novus Biologicals
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PAR4 Antibody - NBP2-26642 from Novus Biologicals
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PAR4 Antibody - NLS1310 from Novus Biologicals
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