F2RL3

Gene Symbol F2RL3
Entrez Gene 9002
Alt Symbol PAR4
Species Human
Gene Type protein-coding
Description coagulation factor II (thrombin) receptor-like 3
Other Description PAR-4|protease-activated receptor-4|proteinase-activated receptor 4|thrombin receptor-like 3
Swissprots O76067 Q6DK42 Q96RI0
Accessions AAK61908 EAW84566 Q96RI0 AF055917 AAC25699 AF080214 AAC28860 AY431102 AAR08487 BC074782 AAH74782 XM_005260139 XP_005260196 NM_003950 NP_003941
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. {ECO:0000269|PubMed:10079109}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets.
Top Pathways Rap1 signaling pathway, Neuroactive ligand-receptor interaction

PAR-4 CRISPR/Cas9 KO Plasmid (h) - sc-401719 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 HDR Plasmid (h) - sc-401719-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 Double Nickase Plasmid (h) - sc-401719-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 Double Nickase Plasmid (h2) - sc-401719-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 CRISPR Activation Plasmid (h) - sc-401719-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 CRISPR Activation Plasmid (h2) - sc-401719-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 Lentiviral Activation Particles (h) - sc-401719-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 Lentiviral Activation Particles (h2) - sc-401719-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PAR-4 siRNA (h) - sc-72068 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAR-4 shRNA Plasmid (h) - sc-72068-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAR-4 shRNA (h) Lentiviral Particles - sc-72068-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PAR4 RNAi - H00009002-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU151081 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN8070 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8070 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09642 from Sigma-Aldrich

Category miRNA

F2RL3 siRNA (Human) - CRH5941 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

F2RL3 - MBS8214805 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human F2 (NM_003950.2) - SHH288429 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human F2RL3(NM_003950.2) - SHH043589 from Creative biogene

Category siRNA
Species Reactivities Human

F2RL3 shRNA Plasmid (Human) - CHH5941 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

F2RL3 miRNA 3'UTR clone - MiUTR1H-03363 from Creative biogene

Species Reactivities Human
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