Gene Symbol | F2RL3 |
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Entrez Gene | 9002 |
Alt Symbol | PAR4 |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor II (thrombin) receptor-like 3 |
Other Description | PAR-4|protease-activated receptor-4|proteinase-activated receptor 4|thrombin receptor-like 3 |
Swissprots | O76067 Q6DK42 Q96RI0 |
Accessions | AAK61908 EAW84566 Q96RI0 AF055917 AAC25699 AF080214 AAC28860 AY431102 AAR08487 BC074782 AAH74782 XM_005260139 XP_005260196 NM_003950 NP_003941 |
Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. {ECO:0000269|PubMed:10079109}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely expressed, with highest levels in lung, pancreas, thyroid, testis and small intestine. Not expressed in brain, kidney, spinal cord and peripheral blood leukocytes. Also detected in platelets. |
Top Pathways | Rap1 signaling pathway, Neuroactive ligand-receptor interaction |
Human Proteinase Activated Receptor 4 protein fragment - ab160289 from Abcam
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F2RL3 / PAR4 Antibody Blocking Peptide - LS-E28226 from LifeSpan Bioscience
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F2RL3 / PAR4 Antibody Blocking Peptide - LS-E28227 from LifeSpan Bioscience
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F2RL3 / PAR4 Antibody Blocking Peptide - LS-E28229 from LifeSpan Bioscience
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F2RL3 / PAR4 Antibody Blocking Peptide - LS-E28230 from LifeSpan Bioscience
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F2RL3 / PAR4 Antibody Blocking Peptide - LS-E24435 from LifeSpan Bioscience
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Proteinase-activated receptor 4 / PAR4 Partial Recombinant Protein - H00009002-Q01 from Novus Biologicals
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PAR4 / F2RL3 - H00009002-Q01-10 from Acris Antibodies
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PAR4 / F2RL3 - H00009002-Q01-25 from Acris Antibodies
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PAR4 / F2RL3 Control Peptide - SP4632CP from Acris Antibodies
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F2RL3 fusion protein - ag13624 from Proteintech Group
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F2RL3 fusion protein - ag13645 from Proteintech Group
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F2RL3 fusion protein - Ag20801 from Proteintech Group
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PAR-4 Peptide - 300118 from ABBIOTEC
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PAR-4 Agonist Peptide Amide - GWB-A11C60 from Genway Biotech
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Recombinant Protease Activated Receptor 4 (PAR4) - RPA127Hu01 from Uscn Life Science Inc.
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Recombinant Protease Activated Receptor 4 (PAR4) - RPA127Ra01 from Uscn Life Science Inc.
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PAR4 (R68) Peptide - BS3238P from Bioworld Technology
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Recombinant Protease Activated Receptor 4 (PAR4) - RPA127Hu01 from Cloud-clone
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F2RL3 Protein - abx163562 from Abbexa
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PAR4 / F2RL3 - TP310404 from Acris Antibodies
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Protease Activated Receptor 4, Recombinant Protein - MBS2031691 from MyBioSource
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PAR4, Peptide - MBS843918 from MyBioSource
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F2RL3 Peptide, Human - M34GP05173H from Creative Peptides
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PAR4 Blocking Peptide - CBP4638 from Cohesion Biosciences
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