Gene Symbol | CHAF1B |
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Entrez Gene | 8208 |
Alt Symbol | CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 |
Species | Human |
Gene Type | protein-coding |
Description | chromatin assembly factor 1, subunit B (p60) |
Other Description | CAF-1 subunit B|CAF-I 60 kDa subunit|CAF-I p60|M-phase phosphoprotein 7|chromatin assembly factor 1 subunit B|chromatin assembly factor I p60 subunit|human chromatin assembly factor-I p60 subunit |
Swissprots | Q13112 Q99548 |
Accessions | BAA89426 BAA95549 EAX09741 Q13112 AJ001856 AK092781 AK313152 BAG35970 AL711314 BC001143 BC021218 AAH21218 JF432525 ADZ15742 U20980 AAA76737 X98262 CAA66915 XM_011529753 XP_011528055 XM_011529754 XP_011528056 XM_011529755 XP_011528057 NM_005441 NP_005432 |
Function | Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. {ECO:0000269|PubMed:9813080}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9614144}. Cytoplasm {ECO:0000269|PubMed:9614144}. Note=DNA replication foci. Cytoplasmic in M phase. |
Human p60 CAF1 full length protein - ab159962 from Abcam
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Human p60 CAF1 protein fragment - ab159963 from Abcam
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CHAF1B / CAF1 Antibody Blocking Peptide - LS-E16720 from LifeSpan Bioscience
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CHAF1B / CAF1 Antibody Blocking Peptide - LS-E16721 from LifeSpan Bioscience
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Recombinant Human CHAF1B Protein - H00008208-P01 from Novus Biologicals
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Recombinant Human CHAF1B Protein - H00008208-Q01 from Novus Biologicals
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CHAF1B-Antibody-C-term-Blocking-Peptide - BP9320b from Abgent, a WuXi AppTec company
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CHAF1B Blocking Peptide - 33R-7279 from Fitzgerald
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CHAF1B Blocking Peptide - 33R-4709 from Fitzgerald
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CAF-1 subunit B - H00008208-P01-10 from Acris Antibodies
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CAF-1 subunit B - H00008208-P01-25 from Acris Antibodies
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CAF-1 subunit B - H00008208-Q01-10 from Acris Antibodies
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CAF-1 subunit B - H00008208-Q01-25 from Acris Antibodies
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Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) - RPJ447Mu01 from Uscn Life Science Inc.
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Recombinant Chromatin Assembly Factor 1, Subunit B (CHAF1B) - RPJ447Mu02 from Uscn Life Science Inc.
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CAF-1 p60 (W93) Peptide - BS2656P from Bioworld Technology
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Recombinant Human Chromatin assembly factor 1 subunit B(CHAF1B) - CSB-YP622638HU CSB-EP622638HU CSB-BP622638HU CSB-MP622638HU from Cusabio
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CAF-1 subunit B - TP302858 from Acris Antibodies
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CHAF1B Recombinant Protein Antigen - NBP1-88235PEP from Novus Biologicals
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CHAF1B Peptide, Human - M34GP03060H from Creative Peptides
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Chromatin assembly factor 1 subunit B (CHAF1B), Recombinant Protein - MBS1438270 from MyBioSource
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Recombinant Human CHAF1B protein, Myc/DDK-tagged - CHAF1B-1205H from Creative Biomart
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