Gene Symbol | CHAF1B |
---|---|
Entrez Gene | 8208 |
Alt Symbol | CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7 |
Species | Human |
Gene Type | protein-coding |
Description | chromatin assembly factor 1, subunit B (p60) |
Other Description | CAF-1 subunit B|CAF-I 60 kDa subunit|CAF-I p60|M-phase phosphoprotein 7|chromatin assembly factor 1 subunit B|chromatin assembly factor I p60 subunit|human chromatin assembly factor-I p60 subunit |
Swissprots | Q13112 Q99548 |
Accessions | BAA89426 BAA95549 EAX09741 Q13112 AJ001856 AK092781 AK313152 BAG35970 AL711314 BC001143 BC021218 AAH21218 JF432525 ADZ15742 U20980 AAA76737 X98262 CAA66915 XM_011529753 XP_011528055 XM_011529754 XP_011528056 XM_011529755 XP_011528057 NM_005441 NP_005432 |
Function | Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. {ECO:0000269|PubMed:9813080}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9614144}. Cytoplasm {ECO:0000269|PubMed:9614144}. Note=DNA replication foci. Cytoplasmic in M phase. |
CAF-1 p60 CRISPR/Cas9 KO Plasmid (h) - sc-405091 from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 HDR Plasmid (h) - sc-405091-HDR from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 Double Nickase Plasmid (h) - sc-405091-NIC from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 Double Nickase Plasmid (h2) - sc-405091-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 CRISPR Activation Plasmid (h) - sc-405091-ACT from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 CRISPR Activation Plasmid (h2) - sc-405091-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 Lentiviral Activation Particles (h) - sc-405091-LAC from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 Lentiviral Activation Particles (h2) - sc-405091-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 siRNA (h) - sc-37735 from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 shRNA Plasmid (h) - sc-37735-SH from Santa Cruz Biotechnology
|
||||||||
CAF-1 p60 shRNA (h) Lentiviral Particles - sc-37735-V from Santa Cruz Biotechnology
|
||||||||
CHAF1B RNAi - H00008208-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU110101 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6030 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6030 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR03986 from Sigma-Aldrich
|
||||||||
CHAF1B siRNA (Human) - CRH5397 from Cohesion Biosciences
|
||||||||
CHAF1B - MBS8211552 from MyBioSource
|
||||||||
shRNA set against Human CHAF1B (NM_005441.2) - SHH262685 from Creative biogene
|
||||||||
Human CHAF1B siRNA - orb265899 from Biorbyt
|
||||||||
CHAF1B shRNA Plasmid (Human) - CHH5397 from Cohesion Biosciences
|
||||||||
CHAF1B miRNA 3'UTR clone - MiUTR1H-02092 from Creative biogene
|