Gene Symbol | MSRB2 |
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Entrez Gene | 22921 |
Alt Symbol | CBS-1, CBS1, CGI-131, MSRB, PILB |
Species | Human |
Gene Type | protein-coding |
Description | methionine sulfoxide reductase B2 |
Other Description | methionine-R-sulfoxide reductase B2, mitochondrial|pilin-like transcription factor |
Swissprots | Q9Y3D2 Q17R44 Q9Y5W6 Q4G1C7 |
Accessions | ACA05998 ACA05999 EAW86133 EAW86134 EAW86135 EAW86136 Q9Y3D2 AF122004 AAD38899 AF151889 AAD34126 BC018030 AAH18030 BC066305 BC117471 AAI17472 BC130380 AAI30381 EU446941 ABZ92470 XM_011519426 XP_011517728 NM_012228 NP_036360 |
Function | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post- translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. {ECO:0000269|PubMed:18424444}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:18424444}. |
Tissue Specificity | Ubiquitous. Detected in retina, ocular ciliary body, skeletal muscle, heart, colon, bone marrow, cerebellum, small intestine, fetal brain, fetal liver, kidney, spinal cord, lung, placenta and prostate. {ECO:0000269|PubMed:10375640, ECO:0000269|PubMed:15914630}. |
MsrB2 (G-12) - sc-163097 from Santa Cruz Biotechnology
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MsrB2 (T-13) - sc-163100 from Santa Cruz Biotechnology
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Anti-MSRB2 antibody - ab175845 from Abcam
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Anti-MSRB2 antibody - ab101513 from Abcam
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Anti-MSRB2 antibody - ab56891 from Abcam
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Anti-MSRB2 / MSRB Antibody (Internal, AP) - LS-C279710 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal, APC) - LS-C279712 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal, FITC) - LS-C279714 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal, Biotin) - LS-C279713 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal, Azide-free, HRP) - LS-C279715 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal) - LS-C327940 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (Internal, PE) - LS-C279716 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody - LS-C62247 from LifeSpan Bioscience
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Anti-MSRB2 / MSRB Antibody (aa44-73) - LS-C164654 from LifeSpan Bioscience
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MSRB2 Antibody - NBP1-86594 from Novus Biologicals
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MSRB2 Antibody (2B7) - H00022921-M01 from Novus Biologicals
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MSRB2 Antibody - NBP2-19420 from Novus Biologicals
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MSRB2 Antibody - H00022921-A01 from Novus Biologicals
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Anti-MSRB2 antibody produced in rabbit - HPA027933 from Sigma-Aldrich
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Monoclonal Anti-MSRB2 antibody produced in mouse - WH0022921M1 from Sigma-Aldrich
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Monoclonal Anti-MSRB2 antibody produced in mouse - SAB1404942 from Sigma-Aldrich
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MSRB2-Antibody-Center- - AP6980c from Abgent, a WuXi AppTec company
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MSRB2-Antibody-monoclonal-M01 - AT2920a from Abgent, a WuXi AppTec company
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MSRB2 Antibody - middle region (OAAB04104) - OAAB04104 from Aviva Systems Biology
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MSRB2 antibody [N1C3] - GTX119117 from GeneTex
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