RBL1

Gene Symbol RBL1
Entrez Gene 5933
Alt Symbol CP107, PRB1, p107
Species Human
Gene Type protein-coding
Description retinoblastoma-like 1
Other Description 107 kDa retinoblastoma-associated protein|cellular protein 107|retinoblastoma-like 1 (p107)|retinoblastoma-like protein 1
Swissprots A8K2W5 P28749 Q9H1M1 Q9H1L5 Q8N5K6 Q4VXA0
Accessions AAD14290 EAW76088 EAW76089 P28749 AK290380 BAF83069 AK308096 AK310870 BC032247 AAH32247 BQ004524 CB115117 DQ890612 ABM92229 DQ893783 ABM84709 L14812 AAA02489 M74547 AAA36397 XM_006723842 XP_006723905 XM_011528955 XP_011527257 XM_011528956 XP_011527258 XM_011528957 XP_011527259 XM_011528958 XP_011527260 XM_011528959 XP_011527261 NM_002895 NP_002886 NM_183404 NP_899662
Function Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Subcellular Location Nucleus {ECO:0000305}.
Top Pathways Cell cycle, TGF-beta signaling pathway, Viral carcinogenesis

RBL1 - MBS1275177 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC032247

Human RBL1 cDNA clone(NM_183404.1) - CDFG012436 from Creative Biomart

Species Human
Accession NM_183404.1

Human RBL1 cDNA clone(NM_002895.2) - CDFH016004 from Creative Biomart

Species Human
Accession NM_002895.2

Human RBL1 ORF Clone(NM_002895.2) - CDCR284345 from Creative Biomart

Species Human
Accession NM_002895.2

Human RBL1 ORF Clone(NM_002895.2) - CDCR284346 from Creative Biomart

Species Human
Accession NM_002895.2

Human RBL1 ORF Clone(NM_183404.1) - CDCR325023 from Creative Biomart

Species Human
Accession NM_183404.1

Human RBL1 ORF Clone(NM_183404.1) - CDCR325024 from Creative Biomart

Species Human
Accession NM_183404.1

Human RBL1 ORF Clone(NM_183404.1) - CDCR325025 from Creative Biomart

Species Human
Accession NM_183404.1

Human RBL1 ORF Clone(NM_002895.2) - CDCR284345 from Creative biogene

Species Human

Human RBL1 ORF Clone(NM_183404.1) - CDCR325025 from Creative biogene

Species Human

Human RBL1 ORF Clone (BC032247) - CDCS411027 from Creative biogene

Species Human
Accession P28749

Human RBL1 ORF Clone (BC141917) - CDCS419364 from Creative biogene

Species Human
Accession P28749

Human RBL1 cDNA Clone(NM_183404.1) - CDFG012436 from Creative biogene

Species Human

Human RBL1 cDNA Clone(NM_002895.2) - CDFH016004 from Creative biogene

Species Human
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