CHPF

Gene Symbol CHPF
Entrez Gene 79586
Alt Symbol CHSY2, CSS2
Species Human
Gene Type protein-coding
Description chondroitin polymerizing factor
Other Description N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II|N-acetylgalactosaminyltransferase 2|chondroitin glucuronyltransferase 2|chondroitin sulfate synthase 2|chondroitin-polymerizing factor|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II
Swissprots Q9H0F8 Q7L4G1 Q8IZ52 Q9H618 Q6UXD6 B4DXU0
Accessions EAW70764 EAW70765 EAW70766 EAW70767 EAW70768 EAW70769 EAW70770 Q8IZ52 AB086063 BAC81536 AB095813 BAC78393 AK026331 BAB15449 AK302124 BAG63502 AL136814 CAB66748 AY358403 AAQ88769 BC008878 AAH08878 BC021223 AAH21223 BC023531 AAH23531 DC341343 XM_011511838 XP_011510140 NM_001195731 NP_001182660 NM_024536 NP_078812
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. {ECO:0000269|PubMed:12761225}.
Subcellular Location Isoform 2: Mitochondrion matrix {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells. {ECO:0000269|PubMed:12716890, ECO:0000269|PubMed:12761225, ECO:0000269|PubMed:22082830}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

CHSY2 (H-70) - sc-98467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CHSY2 (H-70): sc-98467. Western blot analysis of CHSY2 expression in non-transfected: sc-117752 (A) and mouse CHSY2 transfected: sc-119254 (B) 293T whole cell lysates.

CHSY2 (E-19) - sc-50548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CHSY2 (N-20) - sc-50549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CHSY2 (N-20): sc-50549. Western blot analysis of CHSY2 expression in non-transfected: sc-117752 (A) and mouse CHSY2 transfected: sc-119254 (B) 293T whole cell lysates.

CHSY2 (P-20) - sc-50550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CHSS2 antibody - ab75052 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CHSS2 antibody (ab75052) at 1/500 dilutionLane 1 : Extracts from LOVO cellsLane 2 : Extracts from K562 cellsLane 3 : Extracts from LOVO cells plus 5µg immunizing peptideLysates/proteins at 5 µg per lane.

Anti-CHPF Antibody (aa33-82) - LS-C201560 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Esophagus Tumor. CHSY2 antibody dilution 1.0 ug/ml.

Anti-CHPF Antibody (aa631-680) - LS-C198801 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human cervix carcinoma tissue, using CHSY2 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-CHPF Antibody (Arg671) - LS-C177362 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of CHSY2 (R671) pAb in paraffin-embedded human cervix carcinoma tissue.

Anti-CHPF Antibody - LS-C168746 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with CHPF Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CHPF Antibody (Internal, AP) - LS-C213300 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal, Biotin) - LS-C213302 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal, APC) - LS-C213301 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal, Azide-free, HRP) - LS-C213304 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal, FITC) - LS-C213303 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal, PE) - LS-C213305 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CHPF Antibody (Internal) - LS-C320365 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

CHSS2 Antibody - NBP1-88087 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CHSS2 Antibody [NBP1-88087] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Negative control (vector only transfected HEK293T lysate)Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403000)

Anti-CHSY2, C-Terminal antibody produced in rabbit - SAB4503161 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>CHSY2 Antibody: <B>Cat. No. SAB4503161</B>: Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using CHSY2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CHPF (46-60) antibody produced in rabbit - SAB1101951 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human CHPF was separated on SDS-PAGE, blotted with Anti-CHPF (46-60) (<B>Cat. No. SAB1101951</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000

Anti-CHPF antibody produced in rabbit - HPA035123 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CHPF: <B>Cat. No. HPA035123</B>: Immunohistochemical staining of human small intestine shows moderate cytoplasmic and membranous positivity in glandular cells.

ANTI-CHPF (CENTER) antibody produced in rabbit - SAB1307223 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CHPF (Center): <B>Cat. No. SAB1307223</B>: Western blot analysis of CHPF Antibody (Center) in MDA-MB435, MCF-7, HepG2, A375 cell line and Mouse testis tissue lysates (35 μg/lane).

CHSY3 Antibody - N-terminal region (ARP49125_P050) - ARP49125_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CHPF-Antibody-Center - AP9046c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CHPF Antibody (Center) (Cat. #AP9046c) in MDA-MB435, MCF-7, HepG2, A375 cell line and mouse testis tissue lysates (35ug/lane). CHPF (arrow) was detected using the purified Pab.

CHPF Antibody - middle region (OAAB05633) - OAAB05633 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CHSY2 antibody - GTX87921 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-CHSY2 antibody used in ICC/IF. GTX87921
Search more