CHPF

Gene Symbol CHPF
Entrez Gene 79586
Alt Symbol CHSY2, CSS2
Species Human
Gene Type protein-coding
Description chondroitin polymerizing factor
Other Description N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II|N-acetylgalactosaminyltransferase 2|chondroitin glucuronyltransferase 2|chondroitin sulfate synthase 2|chondroitin-polymerizing factor|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II
Swissprots Q9H0F8 Q7L4G1 Q8IZ52 Q9H618 Q6UXD6 B4DXU0
Accessions EAW70764 EAW70765 EAW70766 EAW70767 EAW70768 EAW70769 EAW70770 Q8IZ52 AB086063 BAC81536 AB095813 BAC78393 AK026331 BAB15449 AK302124 BAG63502 AL136814 CAB66748 AY358403 AAQ88769 BC008878 AAH08878 BC021223 AAH21223 BC023531 AAH23531 DC341343 XM_011511838 XP_011510140 NM_001195731 NP_001182660 NM_024536 NP_078812
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. {ECO:0000269|PubMed:12761225}.
Subcellular Location Isoform 2: Mitochondrion matrix {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells. {ECO:0000269|PubMed:12716890, ECO:0000269|PubMed:12761225, ECO:0000269|PubMed:22082830}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

CHPF overexpression lysate - LY403000 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CHPF 293 Cell Lysate - 402610 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CHSS2 Overexpression Lysate (Native) - NBL1-09169 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CHSS2 Overexpression Lysate (Adult Normal) [NBL1-09169] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CHSS2.

CHPF Over-expression Lysate Product - GWB-58A82E from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human CHPF Knockdown Stable Cell Line - CSC-DC003116 from Creative biogene

Category Cell Line
Species Human
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