CHPF

Gene Symbol CHPF
Entrez Gene 79586
Alt Symbol CHSY2, CSS2
Species Human
Gene Type protein-coding
Description chondroitin polymerizing factor
Other Description N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II|N-acetylgalactosaminyltransferase 2|chondroitin glucuronyltransferase 2|chondroitin sulfate synthase 2|chondroitin-polymerizing factor|glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II
Swissprots Q9H0F8 Q7L4G1 Q8IZ52 Q9H618 Q6UXD6 B4DXU0
Accessions EAW70764 EAW70765 EAW70766 EAW70767 EAW70768 EAW70769 EAW70770 Q8IZ52 AB086063 BAC81536 AB095813 BAC78393 AK026331 BAB15449 AK302124 BAG63502 AL136814 CAB66748 AY358403 AAQ88769 BC008878 AAH08878 BC021223 AAH21223 BC023531 AAH23531 DC341343 XM_011511838 XP_011510140 NM_001195731 NP_001182660 NM_024536 NP_078812
Function Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress. {ECO:0000269|PubMed:12761225}.
Subcellular Location Isoform 2: Mitochondrion matrix {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells. {ECO:0000269|PubMed:12716890, ECO:0000269|PubMed:12761225, ECO:0000269|PubMed:22082830}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

CHSY2 CRISPR/Cas9 KO Plasmid (h) - sc-408954 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 HDR Plasmid (h) - sc-408954-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 Double Nickase Plasmid (h) - sc-408954-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 Double Nickase Plasmid (h2) - sc-408954-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 CRISPR Activation Plasmid (h) - sc-408954-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 CRISPR Activation Plasmid (h2) - sc-408954-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 Lentiviral Activation Particles (h) - sc-408954-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 Lentiviral Activation Particles (h2) - sc-408954-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHSY2 siRNA (h) - sc-60381 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHSY2 shRNA Plasmid (h) - sc-60381-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHSY2 shRNA (h) Lentiviral Particles - sc-60381-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU139261 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6084 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6084 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03584 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03584

CHPF siRNA (Human) - CRJ2409 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHPF - MBS8204182 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHPF (NM_024536.5) - SHH263345 from Creative biogene

Category siRNA
Species Reactivities Human

CHPF shRNA Plasmid (Human) - CHJ2409 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHPF miRNA 3'UTR clone - MiUTR1H-02130 from Creative biogene

Species Reactivities Human
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