BLOC1S1

Gene Symbol BLOC1S1
Entrez Gene 2647
Alt Symbol BLOS1, GCN5L1, MICoA, RT14
Species Human
Gene Type protein-coding
Description biogenesis of lysosomal organelles complex-1, subunit 1
Other Description BLOC subunit 1|BLOC-1 subunit 1|GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1|GCN5 general control of amino-acid synthesis 5-like 1|GCN5-like protein 1|MTA1-interacting coactivator|biogenesis of lysosome-related organelles complex 1 subunit 1
Swissprots P78537 Q6NZ45 A1L4Q9
Accessions EAW96824 P78537 AI673441 AI816035 AK307069 BC066340 BC130640 AAI30641 BC132795 AAI32796 BQ899204 BU601406 CN263524 D64007 BAA10887 DA243440 DA864590 S82447 AAB37682 NR_037656 NR_037657 NM_001487 NP_001478 NR_037655
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9. {ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:22309213}.
Subcellular Location Mitochondrion intermembrane space {ECO:0000269|PubMed:22309213}. Mitochondrion matrix {ECO:0000269|PubMed:22309213}. Cytoplasm, cytosol {ECO:0000269|PubMed:22309213}.

BLOS1 (C-18) - sc-167208 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BLOS1 (C-18): sc-167208. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

Anti-BLOC1S1 antibody - ab121669 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121669 at 1/25 dilution staining BLOC1S1 in Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

Anti-BLOC1S1 Antibody (aa22-71) - LS-C186668 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Lung Tumor. BLOC1S1 antibody dilution 1.0 ug/ml.

Anti-BLOC1S1 Antibody - LS-C211666 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16 kDa. Observed band size: 75 kDa.

Anti-BLOC1S1 Antibody (HRP) - LS-C211667 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16 kDa. Observed band size: 75 kDa.

Anti-BLOC1S1 Antibody (FITC) - LS-C211669 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16 kDa. Observed band size: 75 kDa.

Anti-BLOC1S1 Antibody (Biotin) - LS-C211670 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 16 kDa. Observed band size: 75 kDa.

BLOC1S1 Antibody - NBP1-88583 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: BLOC1S1 Antibody [NBP1-88583] - Staining of human duodenum shows cytoplasmic positivity in glandular cells.

Anti-BLOC1S1 antibody produced in rabbit - HPA021381 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BLOC1S1: <B>Cat. No. HPA021381</B>: Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

BLOC1S1 Antibody - N-terminal region (ARP38042_P050) - ARP38042_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BLOC1S1 antibody - 70R-21463 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

BLOC1 antibody - 70R-15337 from Fitzgerald

Host Rabbit
Clonality Polyclonal

Biogenesis of lysosome-related organelles complex 1 subunit 1 antibody (Biotin) - orb240224 from Biorbyt

Prices $400.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

BLOC1 antibody (biotin) - 60R-1840 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

BLOC1 antibody (HRP) - 60R-1838 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

BLOC1 antibody (FITC) - 60R-1839 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

BLOC1S1 Antibody - abx111228 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

BLOC1S1 Antibody (Biotin) - abx105192 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

BLOC1S1 Antibody (HRP) - abx108026 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

BLOS1 Antibody - abx109579 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

BLOS1 Antibody (FITC) - abx106609 from Abbexa

Prices $490.00, $490.00, $490.00, $490.00
Sizes 10 μl, 50 μl, 100 μl, 200 μl
Host Rabbit
Clonality Polyclonal

BLOC-1 subunit 1 antibody - 19687-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human small intestine slide using 19687-1-AP( BLOC1S1-Specific Antibody) at dilution of 1:50

Anti-Biogenesis of lysosome-related organelles complex 1 subunit 1 - 15-1077-1 from ARP American Research Products

Prices $129.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Biogenesis of lysosome-related organelles complex 1 subunit 1, Biotin - 15-1077-2 from ARP American Research Products

Prices $149.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Biogenesis of lysosome-related organelles complex 1 subunit 1, FITC - 15-1077-3 from ARP American Research Products

Prices $149.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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