BLOC1S1

Gene Symbol	BLOC1S1
Entrez Gene	2647
Alt Symbol	BLOS1, GCN5L1, MICoA, RT14
Species	Human
Gene Type	protein-coding
Description	biogenesis of lysosomal organelles complex-1, subunit 1
Other Description	BLOC subunit 1|BLOC-1 subunit 1|GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1|GCN5 general control of amino-acid synthesis 5-like 1|GCN5-like protein 1|MTA1-interacting coactivator|biogenesis of lysosome-related organelles complex 1 subunit 1
Swissprots	P78537 Q6NZ45 A1L4Q9
Accessions	EAW96824 P78537 AI673441 AI816035 AK307069 BC066340 BC130640 AAI30641 BC132795 AAI32796 BQ899204 BU601406 CN263524 D64007 BAA10887 DA243440 DA864590 S82447 AAB37682 NR_037656 NR_037657 NM_001487 NP_001478 NR_037655
Function	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9. {ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:22309213}.
Subcellular Location	Mitochondrion intermembrane space {ECO:0000269|PubMed:22309213}. Mitochondrion matrix {ECO:0000269|PubMed:22309213}. Cytoplasm, cytosol {ECO:0000269|PubMed:22309213}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), Human, ELISA Kit - CSB-EL002718HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), Human, ELISA Kit - E01B0700 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), Human, ELISA Kit - E01B0806 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

biogenesis of lysosomal organelles complex-1, subunit 1, ELISA Kit - MBS938424 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human BLOC1S1 is typically less than 4.68 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 18.75 pg/ml -1200 pg/ml.

Biogenesis of lysosome related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7228353 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7251216 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7245338 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7203872 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7243079 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7215455 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7224181 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7232641 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7200651 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7239316 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7218330 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), ELISA Kit - MBS7247592 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Biogenesis of lysosome-related organelles complex 1 subunit 1(BLOC1S1) ELISA kit - CSB-EL002718HU from Cusabio Category ELISA Kit Sensitivity 4.68pg/ml Range 18.75 pg/ml-1200 pg/ml

Human Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1) ELISA Kit - EKC32877 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

Human BLOC1S1 ELISA Kit - E004990 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human BLOC1S1 is typically less than 4.68 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the

BLOC1S1 ELISA Kit (Human) (OKCA01127) - OKCA01127 from Aviva Systems Biology Category ELISA Kit Prices $600.00 Sizes 96 wells Sensitivity 4.68 pg/mL Range 18.75 - 1,200 pg/mL

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