BLOC1S1

Gene Symbol	BLOC1S1
Entrez Gene	2647
Alt Symbol	BLOS1, GCN5L1, MICoA, RT14
Species	Human
Gene Type	protein-coding
Description	biogenesis of lysosomal organelles complex-1, subunit 1
Other Description	BLOC subunit 1|BLOC-1 subunit 1|GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1|GCN5 general control of amino-acid synthesis 5-like 1|GCN5-like protein 1|MTA1-interacting coactivator|biogenesis of lysosome-related organelles complex 1 subunit 1
Swissprots	P78537 Q6NZ45 A1L4Q9
Accessions	EAW96824 P78537 AI673441 AI816035 AK307069 BC066340 BC130640 AAI30641 BC132795 AAI32796 BQ899204 BU601406 CN263524 D64007 BAA10887 DA243440 DA864590 S82447 AAB37682 NR_037656 NR_037657 NM_001487 NP_001478 NR_037655
Function	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9. {ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:22309213}.
Subcellular Location	Mitochondrion intermembrane space {ECO:0000269|PubMed:22309213}. Mitochondrion matrix {ECO:0000269|PubMed:22309213}. Cytoplasm, cytosol {ECO:0000269|PubMed:22309213}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BLOC1S1 full length protein - ab152418 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human BLOC1S1 protein fragment - ab152419 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BLOC1S1 Antibody Blocking Peptide - LS-E13644 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BLOC1S1 Protein - H00002647-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BLOC1S1 Protein - H00002647-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 1 protein (OPCA00336) - OPCA00336 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Human FLJ39337 protein - orb245035 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BLOC-1 subunit 1 - H00002647-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

BLOC-1 subunit 1 - H00002647-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BLOC-1 subunit 1 - H00002647-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BLOC-1 subunit 1 - H00002647-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 1 - CSB-EP004954h CSB-BP004954h CSB-MP004954h from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant human Biogenesis of lysosome-related organelles complex 1 subunit 1 - CSB-RP004954h from Cusabio Category Protein Species Human

Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 1(BLOC1S1) - CSB-YP002718HU CSB-EP002718HU CSB-BP002718HU CSB-MP002718HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Biogenesis of lysosome-related organelles complex 1 subunit 1 protein - RPC140215 from Biomatik Category Protein Prices $299.20, $352.00, $550.00, $687.50, $997.50, $1,507.50 Sizes 10 µg, 50 µg, 100 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

BLOC1S1 Protein - abx164254 from Abbexa Category Protein Species Human, Mouse, Rat

BLOC-1 subunit 1 - TP324412 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

BLOC1S1 Recombinant Protein Antigen - NBP1-88583PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BLOC1S1 Peptide, Human - M34GP01457H from Creative Peptides Category Peptide Source Synthetic. Species Human

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), Recombinant Protein - MBS950528 from MyBioSource Category Protein Prices $895.00, $895.00, $1,120.00, $1,120.00, $1,315.00, $1,315.00, $1,770.00, $1,770.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC1S1), Recombinant Protein - MBS1325367 from MyBioSource Category Protein Prices $895.00, $895.00, $1,120.00, $1,120.00, $1,315.00, $1,315.00, $1,770.00, $1,770.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Biogenesis of lysosome-related organelles complex 1 subunit 1 protein, Recombinant Protein - MBS717136 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli

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