NTSR1

Gene Symbol NTSR1
Entrez Gene 4923
Alt Symbol NTR
Species Human
Gene Type protein-coding
Description neurotensin receptor 1 (high affinity)
Other Description NT-R-1|NTR1|NTRH|high-affinity levocabastine-insensitive neurotensin receptor|neurotensin receptor type 1
Swissprots Q9H4H1 P30989 Q9H4T5
Accessions CAJ34549 EAW75345 P30989 AY429106 AAR07901 BC040711 BC152809 AAI52810 X70070 CAA49675 XM_011528827 XP_011527129 NM_002531 NP_002522
Function G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis. {ECO:0000269|PubMed:21725197, ECO:0000269|PubMed:23140271, ECO:0000269|PubMed:8381365}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Membrane raft. Note=Palmitoylation is required for localization at CAV1-enriched membrane rafts.
Tissue Specificity Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain. {ECO:0000269|PubMed:20048080, ECO:0000269|PubMed:8381365}.
Top Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

NTR1 CRISPR/Cas9 KO Plasmid (h) - sc-402552 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 HDR Plasmid (h) - sc-402552-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 Double Nickase Plasmid (h) - sc-402552-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 Double Nickase Plasmid (h2) - sc-402552-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 CRISPR Activation Plasmid (h) - sc-402552-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 CRISPR Activation Plasmid (h2) - sc-402552-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 Lentiviral Activation Particles (h) - sc-402552-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 Lentiviral Activation Particles (h2) - sc-402552-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NTR1 siRNA (h) - sc-36103 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NTR1 shRNA Plasmid (h) - sc-36103-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NTR1 shRNA (h) Lentiviral Particles - sc-36103-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15572 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15572 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11474 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11474

NTSR1 siRNA (Human) - CRH3273 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Neurotensin Receptor 1 RNAi - H00004923-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NTSR1 (NM_002531.2) - SHH355828 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NTSR1(NM_002531.2) - SHR009092 from Creative biogene

Category siRNA
Species Reactivities Human

NTSR1 shRNA Plasmid (Human) - CHH3273 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NTSR1 miRNA 3'UTR clone - MiUTR1H-06953 from Creative biogene

Species Reactivities Human
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