ELL2

Gene Symbol	ELL2
Entrez Gene	22936
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	elongation factor, RNA polymerase II, 2
Other Description	ELL-related RNA polymerase II, elongation factor|RNA polymerase II elongation factor ELL2
Swissprots	B4DNK7 O00472
Accessions	AAC51232 EAW96060 O00472 AB209343 BAD92580 AK296870 BAG59433 AK297956 BAG60269 AK300310 BAG62063 AV652801 BC028412 AAH28412 BC151238 BX538289 CAD98084 DQ891536 ABM82462 DQ894725 ABM85651 XM_006714575 XP_006714638 XM_011543280 XP_011541582 NM_012081 NP_036213
Function	Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:22195968, ECO:0000269|PubMed:23251033}.
Subcellular Location	Nucleus.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ELL2 protein fragment - ab161484 from Abcam Category Protein Source Wheat germ Species Human

ELL2 Antibody Blocking Peptide - LS-E4115 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ELL2 Antibody Blocking Peptide - LS-E14032 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ELL2 Protein - H00022936-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ELL2-Antibody-C-term-Blocking-Peptide - BP16355b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ELL2 - H00022936-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ELL2 - H00022936-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ELL2 fusion protein - ag3428 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ELL2 fusion protein - Ag9135 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human RNA polymerase II elongation factor ELL2(ELL2) - CSB-YP007609HU CSB-EP007609HU CSB-BP007609HU CSB-MP007609HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ELL2 Protein - NBP1-89494PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ELL2 Peptide, Human - M34GP04864H from Creative Peptides Category Peptide Source Synthetic. Species Human

RNA polymerase II elongation factor ELL2 (ELL2), Recombinant Protein - MBS1229314 from MyBioSource Category Protein Prices $1,440.00, $1,440.00, $1,665.00, $1,665.00, $2,440.00, $2,440.00, $2,880.00, $2,880.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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