ELL2

Gene Symbol ELL2
Entrez Gene 22936
Alt Symbol -
Species Human
Gene Type protein-coding
Description elongation factor, RNA polymerase II, 2
Other Description ELL-related RNA polymerase II, elongation factor|RNA polymerase II elongation factor ELL2
Swissprots B4DNK7 O00472
Accessions AAC51232 EAW96060 O00472 AB209343 BAD92580 AK296870 BAG59433 AK297956 BAG60269 AK300310 BAG62063 AV652801 BC028412 AAH28412 BC151238 BX538289 CAD98084 DQ891536 ABM82462 DQ894725 ABM85651 XM_006714575 XP_006714638 XM_011543280 XP_011541582 NM_012081 NP_036213
Function Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:22195968, ECO:0000269|PubMed:23251033}.
Subcellular Location Nucleus.

ELL2 CRISPR/Cas9 KO Plasmid (h) - sc-404784 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 HDR Plasmid (h) - sc-404784-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 Double Nickase Plasmid (h) - sc-404784-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 Double Nickase Plasmid (h2) - sc-404784-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 CRISPR Activation Plasmid (h) - sc-404784-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 CRISPR Activation Plasmid (h2) - sc-404784-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 Lentiviral Activation Particles (h) - sc-404784-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 Lentiviral Activation Particles (h2) - sc-404784-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ELL2 siRNA (h) - sc-77259 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELL2 shRNA Plasmid (h) - sc-77259-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ELL2 shRNA (h) Lentiviral Particles - sc-77259-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU104961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7810 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7810 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ELL2 siRNA (Human) - CRH7886 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELL2 RNAi - H00022936-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

ELL2 - MBS8223766 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ELL2 (NM_012081.5) - SHH285125 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ELL2(NM_012081.5) - SHG209773 from Creative biogene

Category siRNA
Species Reactivities Human

Human ELL2 siRNA - orb268388 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ELL2 shRNA Plasmid (Human) - CHH7886 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ELL2 miRNA 3'UTR clone - MiUTR1H-03196 from Creative biogene

Species Reactivities Human
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