ELL2

Gene Symbol ELL2
Entrez Gene 22936
Alt Symbol -
Species Human
Gene Type protein-coding
Description elongation factor, RNA polymerase II, 2
Other Description ELL-related RNA polymerase II, elongation factor|RNA polymerase II elongation factor ELL2
Swissprots B4DNK7 O00472
Accessions AAC51232 EAW96060 O00472 AB209343 BAD92580 AK296870 BAG59433 AK297956 BAG60269 AK300310 BAG62063 AV652801 BC028412 AAH28412 BC151238 BX538289 CAD98084 DQ891536 ABM82462 DQ894725 ABM85651 XM_006714575 XP_006714638 XM_011543280 XP_011541582 NM_012081 NP_036213
Function Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:22195968, ECO:0000269|PubMed:23251033}.
Subcellular Location Nucleus.

ELL2 (G-5) - sc-376611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ELL2 (G-5): sc-376611. Western blot analysis of ELL2 expression in ES-2 (A) and HeLa (B) whole cell lysates.

ELL2 (C-12) - sc-83806 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ELL2 (M-86) - sc-98405 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ELL2 (N-14) - sc-83808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ELL2 (N-14): sc-83808. Western blot analysis of ELL2 expression in ES-2 whole cell lysate.

ELL2 (H-85) - sc-98406 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ELL2 antibody - ab115027 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ELL2 antibody (ab115027) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-ELL2 antibody - ab194445 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-ELL2 antibody (ab194445) at 1/1000 dilution + ELL2 recombinant protein (immunizing peptide) at 0.2 µg

Anti-ELL2 antibody - ab129439 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ELL2 antibody (ab129439) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

Anti-ELL2 antibody - ab111436 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ELL2 antibody (ab111436) at 1 µg/ml + ACHN cell lysate at 10 µg

Anti-ELL2 Antibody - LS-C65252 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-ELL2 Antibody (clone ELL2A11H2) - LS-C184343 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ELL2A11H2

Anti-ELL2 Antibody (aa450-479, Biotin) - LS-C256629 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa450-479, AP) - LS-C256626 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa450-479, APC) - LS-C256628 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa450-479, FITC) - LS-C256630 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa450-479, Azide-free, HRP) - LS-C256631 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa450-479, PE) - LS-C256632 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (aa448-497) - LS-C198916 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using ELL2 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-ELL2 Antibody (aa449-479) - LS-C321087 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ELL2 Antibody (C-Terminus) - LS-C135067 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ELL2 antibody LS-C135067 Western blot of ACHN lysate.

Anti-ELL2 Antibody (aa400-450) - LS-C289239 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse ELL2 by Western Blot. Samples: Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-ELL2 antibody used for WB at 0.5 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-ELL2 Antibody (aa450-479) - LS-C167731 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ELL2 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The ELL2 antibody detected the ELL2 protein (arrow).

Anti-ELL2 Antibody (clone ELL2A11H2) - LS-C342396 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ELL2A11H2
Western blot analysis of immunized recombinant protein, using anti-ELL2 monoclonal antibody.

ELL2 Antibody - NBP1-89494 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELL2 Antibody [NBP1-89494] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human plasma (IgG/HSA depleted)<br/>Lane 5: Human liver tissue<br/>Lane 6: Human tonsil tissue

ELL2 Antibody - NBP1-69220 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ELL2 Antibody [NBP1-69220] - ACHN cell lysate, concentration 0.2-1 ug/ml.
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