Gene Symbol | OLAH |
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Entrez Gene | 55301 |
Alt Symbol | AURA1, SAST, THEDC1 |
Species | Human |
Gene Type | protein-coding |
Description | oleoyl-ACP hydrolase |
Other Description | S-acyl fatty acid synthase thioesterase, medium chain|augmented in rheumatoid arthritis 1|thioesterase II|thioesterase domain containing 1|thioesterase domain-containing protein 1 |
Swissprots | Q9NUW1 Q5VUB6 Q9NV23 |
Accessions | CAE89822 EAW86244 EAW86245 Q9NV23 AK001844 BAA91937 AK001968 BAA92007 BC050372 AAH50372 BG281536 BG722790 BI830605 BR000403 FAA00320 HQ448637 ADQ33115 XM_006717456 XP_006717519 NM_001039702 NP_001034791 NM_018324 NP_060794 |
Function | In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity). {ECO:0000250}. |
Tissue Specificity | Isoform 2 is up-regulated in bone marrow- derived mononuclear cells of rheumatoid arthritis patients. {ECO:0000269|PubMed:17082220}. |
Top Pathways | Fatty acid biosynthesis |
OLAH Antibody Blocking Peptide - LS-E20398 from LifeSpan Bioscience
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OLAH Antibody Blocking Peptide - LS-E20397 from LifeSpan Bioscience
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OLAH Blocking Peptide - 33R-6030 from Fitzgerald
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OLAH Blocking Peptide - 33R-6029 from Fitzgerald
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OLAH fusion protein - Ag13194 from Proteintech Group
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OLAH fusion protein - Ag11694 from Proteintech Group
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Recombinant Human OLAH, His-tagged - OLAH-1451H from Creative Biomart
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Recombinant Human S-acyl fatty acid synthase thioesterase, medium chain(OLAH) - CSB-YP878894HU CSB-EP878894HU CSB-BP878894HU CSB-MP878894HU from Cusabio
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OLAH / THEDC1 (transcript variant 2) - TP308251 from Acris Antibodies
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OLAH Recombinant Protein Antigen - NBP1-83780PEP from Novus Biologicals
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OLAH Recombinant Protein Antigen - NBP1-83779PEP from Novus Biologicals
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OLAH Peptide, Human - M34GP10829H from Creative Peptides
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S-acyl fatty acid synthase thioesterase, medium chain (OLAH), Recombinant Protein - MBS1452135 from MyBioSource
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