OLAH

Gene Symbol OLAH
Entrez Gene 55301
Alt Symbol AURA1, SAST, THEDC1
Species Human
Gene Type protein-coding
Description oleoyl-ACP hydrolase
Other Description S-acyl fatty acid synthase thioesterase, medium chain|augmented in rheumatoid arthritis 1|thioesterase II|thioesterase domain containing 1|thioesterase domain-containing protein 1
Swissprots Q9NUW1 Q5VUB6 Q9NV23
Accessions CAE89822 EAW86244 EAW86245 Q9NV23 AK001844 BAA91937 AK001968 BAA92007 BC050372 AAH50372 BG281536 BG722790 BI830605 BR000403 FAA00320 HQ448637 ADQ33115 XM_006717456 XP_006717519 NM_001039702 NP_001034791 NM_018324 NP_060794
Function In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex. The chain length of the released fatty acid is usually C16. However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2) (By similarity). {ECO:0000250}.
Tissue Specificity Isoform 2 is up-regulated in bone marrow- derived mononuclear cells of rheumatoid arthritis patients. {ECO:0000269|PubMed:17082220}.
Top Pathways Fatty acid biosynthesis

AURA1 (D-12) - sc-136572 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AURA1 (D-12): sc-136572. Western blot analysis of AURA1 expression in non-transfected: sc-117752 (A) and human AURA1 transfected: sc-116094 (B) 293T whole cell lysates.

AURA1 (G-16) - sc-136573 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-OLAH antibody - ab94441 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-OLAH antibody (ab94441) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal small intestine lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-OLAH Antibody (aa35-84) - LS-C111865 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
OLAH antibody LS-C111865 Western blot of HT1080 cell lysate.

Anti-OLAH Antibody (aa35-84) - LS-C111864 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
OLAH antibody LS-C111864 Western blot of Fetal Small Intestine lysate.

OLAH Antibody - NBP1-83780 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OLAH Antibody [NBP1-83780] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

OLAH Antibody - NBP1-83779 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OLAH Antibody [NBP1-83779] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue

OLAH Antibody - NBP1-56829 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: OLAH Antibody [NBP1-56829] - Human Small Intestine, concentration 0.2-1 ug/ml.

Anti-OLAH, (N-terminal) antibody produced in rabbit - SAB2104377 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-OLAH, antibody produced in rabbit: <B>Cat. No. SAB2104377</B>: Immunoblotting analysis of OLAH in fetal Small intestine with OLAH anitbody at 1 μg/mL.

Anti-OLAH antibody produced in rabbit - HPA037948 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-OLAH: <B>Cat. No. HPA037948</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-OLAH, (N-terminal) antibody produced in rabbit - SAB2104378 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-OLAH, antibody produced in rabbit: <B>Cat. No. SAB2104378</B>: Immunoblotting analysis of OLAH in HT1080 cell lysate with OLAH anitbody at 1 μg/mL.

Anti-OLAH (1-15) antibody produced in rabbit - SAB1102338 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human OLAH was separated on SDS-PAGE, blotted with Anti-OLAH (1-15) (<B>Cat. No. SAB1102338</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + OLAH immunizing peptide (human, 1-15)

OLAH antibody - N-terminal region (ARP56263_P050) - ARP56263_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OLAH antibody - N-terminal region (ARP56264_P050) - ARP56264_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

OLAH antibody - GTX122731 from GeneTex

Host Rabbit
Clonality Polyclonal
Anti-OLAH antibody used in WB-Ag. GTX122731

OLAH antibody, N-term - GTX45079 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

OLAH antibody, N-term - GTX45080 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal

OLAH antibody - 70R-4310 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OLAH antibody - 17676-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

OLAH Antibody - GWB-MU231F from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OLAH Antibody - GWB-MU230E from Genway Biotech

Prices $368.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OLAH, Polyclonal Antibody - MBS5303043 from MyBioSource

Prices $455.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

OLAH, Polyclonal Antibody - MBS5301777 from MyBioSource

Prices $455.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-OLAH (131-145) antibody produced in rabbit - SAB1102339 from Sigma-Aldrich

Prices $307.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human OLAH was separated on SDS-PAGE, blotted with Anti-OLAH (131-145) (<B>Cat. No. SAB1102339</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000 <BR/>2. Antibody dilution 1:1,000 + OLAH immunizing peptide (human, 131-145)

Anti-OLAH antibody produced in rabbit - HPA037947 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-OLAH: <B>Cat. No. HPA037947</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
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