CHD1

Gene Symbol	CHD1
Entrez Gene	1105
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	chromodomain helicase DNA binding protein 1
Other Description	ATP-dependent helicase CHD1|CHD-1|chromodomain-helicase-DNA-binding protein 1
Swissprots	O14646 Q17RZ3
Accessions	CCQ43133 EAW96098 O14646 AF006513 AAB87381 AK094871 BAG52945 BC054860 AAH54860 BC117134 AAI17135 BM698633 BQ436172 BX648767 CN277742 XM_005271866 XP_005271923 XM_005271867 XP_005271924 XM_011543112 XP_011541414 XR_427702 XR_948231 NM_001270 NP_001261
Function	ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells. {ECO:0000250, ECO:0000269|PubMed:18042460}.
Subcellular Location	Nucleus. Cytoplasm {ECO:0000250}. Note=Is released into the cytoplasm when cells enter mitosis and is reincorporated into chromatin during telophase-cytokinesis. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Chd1 protein fragment - ab117050 from Abcam Category Protein Source Wheat germ Species Human

CHD1 Antibody Blocking Peptide - LS-E12171 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHD1 Antibody Blocking Peptide - LS-E26357 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHD1 Partial Recombinant Protein - H00001105-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CHD1 (C Terminus) blocking peptide - GTX89056-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

CHD1 (internal) blocking peptide - GTX88796-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

CHD1 Peptide - AC21-1192-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CHD1 - H00001105-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CHD1 - H00001105-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CHD1 Peptide - 46-641P from ProSci Category Peptide

Recombinant Human CHD1 - CHD1-27812TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Chromodomain-helicase-DNA-binding protein 1(CHD1) ,partial - CSB-YP005325HU CSB-EP005325HU CSB-BP005325HU CSB-MP005325HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CHD1 Protein - abx163968 from Abbexa Category Protein Species Human

CHD1, Peptide - MBS428169 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

CHD1 (internal), Peptide - MBS425877 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog

CHD1 Protein - NBP2-14478PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CHD1 Antibody - SH-A11041 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

CHD1 antibody ( pAb ) , 100 ul - HM-AB1146 from Novatein Biosciences Prices $442.00 Sizes 100 µl

CHD1 antibody ( pAb ) , 10 ul - HM-AB1147 from Novatein Biosciences Prices $91.00 Sizes 10 µl

CHD1 antibody ( mAb ) , 100 ug - HM-AB1148 from Novatein Biosciences Prices $442.00 Sizes 100 µg

CHD1 antibody ( mAb ) , 10 ug - HM-AB1149 from Novatein Biosciences Prices $91.00 Sizes 10 µg

CHD1 Peptide, Human - M34GP03071H from Creative Peptides Category Peptide Source Synthetic. Species Human

CHD1 Immunizing peptide - orb50333 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg

Chromodomain-helicase-DNA-binding protein 1 (CHD1), partial, Recombinant Protein - MBS1093455 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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