Gene Symbol | DDX60 |
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Entrez Gene | 55601 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
Other Description | DEAD box protein 60|probable ATP-dependent RNA helicase DDX60 |
Swissprots | Q9NVE3 Q6PK35 Q8IY21 |
Accessions | CAH61673 EAX04806 EAX04807 EAX04808 EAX04809 Q8IY21 AK000042 BAA90901 AK001649 BAA91809 AK026333 BAB15451 AK223184 BAD96904 AK225191 AK307404 AL137464 CAB70751 BC007820 AAH07820 BC020601 AAH20601 BC038115 AAH38115 BC074781 AAH74781 BX648655 CAE46197 XM_011532103 XP_011530405 XM_011532104 XP_011530406 NM_017631 NP_060101 |
Function | Positively regulates DDX58/RIG-I- and IFIH1/MDA5- dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). {ECO:0000269|PubMed:21478870, ECO:0000269|PubMed:21791617}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21791617}. |
Tissue Specificity | Brain, lymph node, prostate, stomach, thyroid, tongue, trachea, uterus, skeletal muscle, spleen, kidney, liver and small intestine. {ECO:0000269|PubMed:21791617}. |
DDX60 (C-18) - sc-242561 from Santa Cruz Biotechnology
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Anti-DDX60 antibody - ab139807 from Abcam
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Anti-DDX60 antibody - ab151217 from Abcam
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Anti-DDX60 Antibody (Internal) - LS-C153619 from LifeSpan Bioscience
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DDX60 Antibody - NBP1-91826 from Novus Biologicals
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Anti-DDX60 antibody produced in rabbit - HPA046952 from Sigma-Aldrich
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Anti-DDX60 antibody produced in rabbit - SAB3500806 from Sigma-Aldrich
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DDX60 (Center) antibody - AP55506PU-N from Acris Antibodies
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DDX60 Antibody - 6945 from ProSci
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DDX60 antibody - 21956-1-AP from Proteintech Group
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Anti-DDX60 (internal region) polyclonal antibody - DPABH-02100 from Creative Diagnostics
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Anti-DDX60 (aa 1160-1244) polyclonal antibody - DPABH-03348 from Creative Diagnostics
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Anti-DDX60 monoclonal antibody - DCABH-200439 from Creative Diagnostics
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DDX60 Polyclonal Antibody - PA5-34442 from Thermo Fisher Scientific
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DDX60, Polyclonal Antibody - MBS153369 from MyBioSource
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DDX60 Antibody - abx122873 from Abbexa
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DDX60 antibody - pab81482 from Covalab
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DDX60-Antibody - ASC11514 from Abgent, a WuXi AppTec company
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DDX60 (Center) antibody - TA319959 from Acris Antibodies
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DDX60 antibody - orb258919 from Biorbyt
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