Gene Symbol | DDX60 |
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Entrez Gene | 55601 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
Other Description | DEAD box protein 60|probable ATP-dependent RNA helicase DDX60 |
Swissprots | Q9NVE3 Q6PK35 Q8IY21 |
Accessions | CAH61673 EAX04806 EAX04807 EAX04808 EAX04809 Q8IY21 AK000042 BAA90901 AK001649 BAA91809 AK026333 BAB15451 AK223184 BAD96904 AK225191 AK307404 AL137464 CAB70751 BC007820 AAH07820 BC020601 AAH20601 BC038115 AAH38115 BC074781 AAH74781 BX648655 CAE46197 XM_011532103 XP_011530405 XM_011532104 XP_011530406 NM_017631 NP_060101 |
Function | Positively regulates DDX58/RIG-I- and IFIH1/MDA5- dependent type I interferon and interferon inducible gene expression in response to viral infection. Binds ssRNA, dsRNA and dsDNA and can promote the binding of DDX58/RIG-I to dsRNA. Exhibits antiviral activity against hepatitis C virus and vesicular stomatitis virus (VSV). {ECO:0000269|PubMed:21478870, ECO:0000269|PubMed:21791617}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21791617}. |
Tissue Specificity | Brain, lymph node, prostate, stomach, thyroid, tongue, trachea, uterus, skeletal muscle, spleen, kidney, liver and small intestine. {ECO:0000269|PubMed:21791617}. |
Human DDX60 full length protein - ab163138 from Abcam
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DDX60 Antibody Blocking Peptide - LS-E31302 from LifeSpan Bioscience
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Recombinant Human DDX60 Protein - H00055601-P01 from Novus Biologicals
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DDX60 - H00055601-P01-10 from Acris Antibodies
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DDX60 - H00055601-P01-25 from Acris Antibodies
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DDX60 (Center) Control Peptide - AP55506CP-N from Acris Antibodies
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DDX60 Peptide - 6945P from ProSci
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DDX60 fusion protein - ag16642 from Proteintech Group
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DDX60 fusion protein - ag17432 from Proteintech Group
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Recombinant Human Probable ATP-dependent RNA helicase DDX60(DDX60) ,partial - CSB-YP816907HU CSB-EP816907HU CSB-BP816907HU CSB-MP816907HU from Cusabio
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Probable ATP-dependent RNA helicase DDX60 (DDX60), partial, Recombinant Protein - MBS1369942 from MyBioSource
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DDX60 Recombinant Protein Antigen - NBP1-91826PEP from Novus Biologicals
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DDX60 Peptide, Human - M34GP04171H from Creative Peptides
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