Gene Symbol | PTGER1 |
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Entrez Gene | 5731 |
Alt Symbol | EP1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin E receptor 1 (subtype EP1), 42kDa |
Other Description | PGE receptor EP1 subtype|PGE receptor, EP1 subtype|PGE2 receptor EP1 subtype|prostaglandin E receptor 1 (subtype EP1), 42kD|prostaglandin E receptor 1, subtype EP1|prostaglandin E2 receptor EP1 subtype|prostanoid EP1 receptor |
Swissprots | Q86VB5 Q5U5U4 Q86UH3 P34995 Q8NHB2 |
Accessions | BAC05723 EAW84422 P34995 AY275470 AAP32302 BC029768 AAH29768 BC039034 AAH39034 BC051286 AAH51286 L22647 AAC37539 NM_000955 NP_000946 |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
EP1 (H-60) - sc-20674 from Santa Cruz Biotechnology
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EP1 (E-16) - sc-22648 from Santa Cruz Biotechnology
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EP1 (L-15) - sc-22646 from Santa Cruz Biotechnology
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EP1 (M-121) - sc-98388 from Santa Cruz Biotechnology
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EP1 (N-20) - sc-16011 from Santa Cruz Biotechnology
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Anti-Prostaglandin E Receptor EP1 antibody - ab133184 from Abcam
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Anti-Prostaglandin E Receptor EP1 antibody - ab183073 from Abcam
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Anti-Prostaglandin E Receptor EP1 antibody - ab93479 from Abcam
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Anti-Prostaglandin E Receptor EP1 antibody - ab140987 from Abcam
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Anti-Prostaglandin E Receptor EP1 antibody - ab78096 from Abcam
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Anti-Prostaglandin E Receptor EP1 antibody - ab48000 from Abcam
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Anti-PTGER1 / EP1 Antibody (Internal) IHC-plus™ - LS-B1744 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A962 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody (C-Terminus) - LS-C23107 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody (C-Terminus) - LS-C23106 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody - LS-C137438 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody (C-Terminus) - LS-C345601 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody (aa387-404) - LS-C312739 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody IHC-plus™ - LS-B6942 from LifeSpan Bioscience
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Anti-PTGER1 / EP1 Antibody - LS-C332285 from LifeSpan Bioscience
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PTGER1 Antibody - NLS962 from Novus Biologicals
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PTGER1 Polyclonal Antibody - bs-6316R from Bioss
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Anti-PTGER1 antibody produced in rabbit - SAB4300877 from Sigma-Aldrich
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PTGER1 Antibody - C-terminal region (ARP63441_P050) - ARP63441_P050 from Aviva Systems Biology
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EP1-receptor--PTGER1-Antibody-internal-region - AF2501a from Abgent, a WuXi AppTec company
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