Gene Symbol | PTGER1 |
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Entrez Gene | 5731 |
Alt Symbol | EP1 |
Species | Human |
Gene Type | protein-coding |
Description | prostaglandin E receptor 1 (subtype EP1), 42kDa |
Other Description | PGE receptor EP1 subtype|PGE receptor, EP1 subtype|PGE2 receptor EP1 subtype|prostaglandin E receptor 1 (subtype EP1), 42kD|prostaglandin E receptor 1, subtype EP1|prostaglandin E2 receptor EP1 subtype|prostanoid EP1 receptor |
Swissprots | Q86VB5 Q5U5U4 Q86UH3 P34995 Q8NHB2 |
Accessions | BAC05723 EAW84422 P34995 AY275470 AAP32302 BC029768 AAH29768 BC039034 AAH39034 BC051286 AAH51286 L22647 AAC37539 NM_000955 NP_000946 |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
Human Prostaglandin E Receptor EP1 full length protein - ab159273 from Abcam
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Human Prostaglandin E Receptor EP1 peptide - ab48047 from Abcam
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PTGER1 / EP1 Antibody Blocking Peptide - LS-E26053 from LifeSpan Bioscience
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PTGER1 / EP1 Antibody Blocking Peptide - LS-E29714 from LifeSpan Bioscience
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Recombinant Human PTGER1 Protein - H00005731-P01 from Novus Biologicals
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EP1 blocking peptide - GTX89382-PEP from GeneTex
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Prostaglandin E Receptor Ep1 Peptide - AC21-0881-P from Abcore
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PTGER1 - H00005731-P01 from Acris Antibodies
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PTGER1 Control Peptide - SP4711CP from Acris Antibodies
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EP1 Receptor Peptide - 45-539P from ProSci
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PTGER1 Peptide - GWB-TK4210 from Genway Biotech
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ChemiSCREEN™ Membrane Preparation Recombinant Human EP 1 Prostanoid Receptor - HTS099M from EMD Millipore
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Composite Endomorphin 1 (EM1) - CPC062Ge01 from Cloud-clone
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OVA Conjugated Endomorphin 1 (EM1) - CPC062Ge21 from Cloud-clone
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Recombinant Prostaglandin E Receptor 1 (EP1) - RPA219Hu01 from Uscn Life Science Inc.
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Prostaglandin E2 receptor EP1 subtype (PTGER1), Recombinant Protein - MBS961372 from MyBioSource
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EP1 receptor/PTGER1, Peptide - MBS426736 from MyBioSource
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Recombinant Prostaglandin E Receptor 1 (EP1) - RPA219Hu01 from Cloud-clone
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PTGER1 Peptide, Human - M34GP12657H from Creative Peptides
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PTGER1 Recombinant Protein (OPCD00796) - OPCD00796 from Aviva Systems Biology
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Prostaglandin E Receptor 1, Recombinant Protein - MBS2033604 from MyBioSource
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Prostaglandin E2 receptor EP1 subtype (PTGER1), Recombinant Protein - MBS7028192 from MyBioSource
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PTGER1 Immunizing peptide - orb17249 from Biorbyt
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